ArticleClinical cardiology2011
Left atrial volume index over late diastolic mitral annulus velocity (LAVi/A') is a useful echo index to identify advanced diastolic dysfunction and predict clinical outcomes.
Article in Clinical cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Left Atrial Coupling Indexes as New Mortality Predictors in Chronic Chagas Disease.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Left Atrial Coupling Index for the Prediction of Atrial Fibrillation and Heart Failure: Current Evidence and Clinical Implications.Current cardiology reports · 2025Review
- Left Atrial Volumetric/Mechanical Coupling Index in Heart Failure With Preserved Ejection Fraction.Journal of the American Heart Association · 2025Observational
- Left Atrial Volumetric/Mechanical Coupling Index Is Ready for Prime Time Across Clinical Scenarios.Journal of the American Heart Association · 2025Article
- Two-dimensional speckle tracking imaging and tissue Doppler imaging can predict subclinical left ventricular systolic and diastolic dysfunctions after chemotherapy for breast cancer.American journal of translational research · 2025Article
- Current and Clinically Relevant Echocardiographic Parameters to Analyze Left Atrial Function.Journal of cardiovascular development and disease · 2024Review
- Left Atrial Coupling Index Predicts Heart Failure in Patients with End Stage Renal Disease.Medicina (Kaunas, Lithuania) · 2024Article
- Assessment of left atrial function provides incremental value: the left atrial volumetric/mechanical coupling index in patients with chronic kidney disease.Frontiers in cardiovascular medicine · 2024Article
- Incremental Prognosis by Left Atrial Functional Assessment: The Left Atrial Coupling Index in Patients With Floppy Mitral Valves.Journal of the American Heart Association · 2022Article
- Left Atrial Coupling Index and Its Prognostic Value in Heart Failure With Reduced Ejection Fraction.Circulation. Cardiovascular imaging · 2021Article
- Discrepancies in Assessing Diastolic Function in Pre-Clinical Heart Failure Using Different Algorithms-A Primary Care Study.Diagnostics (Basel, Switzerland) · 2020Article
- Atrial Fibrillation Predictors on Mobile Cardiac Telemetry in Cryptogenic Ischemic Stroke.The Neurohospitalist · 2018Article
- Clinical implication of LAVI over A' ratio in patients with acute coronary syndrome.Heart Asia · 2018Article
- Diastolic Heart Failure Predicted by Left Atrial Expansion Index in Patients with Severe Diastolic Dysfunction.PloS one · 2016Article
- Ergospirometry and echocardiography in early stage of heart failure with preserved ejection fraction and in healthy individuals.Arquivos brasileiros de cardiologia · 2015Article
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10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCombined interpretation of late diastolic mitral annulus velocity (A') with left atrial volume index (LAVi) may have additional benefits in the assessment of diastolic dysfunction. HYPOTHESIS: The LAVi/A' ratio may be useful in the identifying advanced diastolic dysfunction (ADD) and predicting clinical outcomes in patients with dyspnea.
methodsWe enrolled 395 consecutive patients hospitalized with dyspnea (New York Heart Association class II-IV) and performed transthoracic Doppler echocardiography and B-type natriuretic peptide (BNP) measurement. LAVi/A' values were evaluated in terms of diagnosing ADD and predicting clinical outcome.
resultsOn the receiver operation characteristic curve analysis for the determination of ADD, the area under the curves of LAVi/A' in the entire population was comparable to those of BNP (0.94 vs 0.93, P = 0.845) and mitral E/E' (0.94 vs 0.93, P = 0.614) and higher than that of LAVi (0.94 vs 0.87; P = 0.014). A LAVi/A' of 4.0 was the best cut-off value to identify ADD. During a median follow-up of 31.9 months (range, 0.3 to 45.7 months), the group with LAVi/A' ≥4.0 had a higher incidence of primary composite outcomes (cardiac death and/or rehospitalization for heart failure) than the group with LAVi/A'<4.0 (25.0% vs 3.3%, P < 0.001). LAVi/A' ≥4.0 was an independent predictor of clinical outcomes (odds ratio, 3.245; 95% confidence interval, 1.386-7.598; P = 0.007).
conclusionsAs a new echo index, LAVi/A' is a useful parameter to identify ADD and predict clinical outcomes in patients with dyspnea.
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