Evidence map›Paper›PMID 21298580›Full record

ArticleCerebellum (London, England)2011

Compartmentation of the cerebellar cortex in the naked mole-rat (Heterocephalus glaber).

Hassan Marzban, Nathan Hoy, Tooka Aavani, Diana K Sarko, Kenneth C Catania, Richard Hawkes

Abstract read
PubMed Publisher
In one paragraph

Article in Cerebellum (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Cerebellar Patterning Defects in Mutant Mice.Frontiers in neuroscience · 2021
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Cellular commitment in the developing cerebellum.Frontiers in cellular neuroscience · 2014
    Review
  8. Article
  9. Cerebellar zones: history, development, and function.Cerebellum (London, England) · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Hassan MarzbanDepartment of Cell Biology and Anatomy, Hotchkiss Brain Institute, and Genes and Development Research Group, Faculty of Medicine, University of Calgary, 3330 Hospital Drive N.W., Calgary, AB, T2N 4N1, Canada.
Nathan Hoy
Tooka Aavani
Diana K Sarko
Kenneth C Catania
Richard Hawkes
University of Calgary · CAVanderbilt University · US

Funding

The organization and plasticity of cortical areas representing the dentitionR01DE016061 · NIDCR · VANDERBILT UNIVERSITY · PI CATANIA, KENNETH CHARLES · 2006 to 2009
$975k
Canadian Institutes of Health ResearchNIDCR NIH HHS DE016061
6 · The paper itself

Abstract

Despite the apparent uniformity in cellular composition of the adult mammalian cerebellar cortex, it is actually highly compartmentalized into transverse zones and within each zone further subdivided into a reproducible array of parasagittal stripes. This basic cerebellar architecture is highly conserved in birds and mammals. However, different species have very different cerebellar morphologies, and it is unclear if cerebellar architecture reflects taxonomic relations or ecological niches. To explore this, we have examined the cerebellum of the naked mole-rat Heterocephalus glaber, a burrowing rodent with adaptations to a subterranean life that include only a rudimentary visual system. The cerebellum of H. glaber resembles that of other rodents with the remarkable exception that cerebellar regions that are prominent in the handling of visual information (the central zone, nodular zone, and dorsal paraflocculus) are greatly reduced or absent. In addition, there is a notable increase in size in the posterior zone, consistent with an expanded role for the trigeminal somatosensory system. These data suggest that cerebellar architecture may be substantially modified to serve a particular ecological niche.

Indexed as

AnimalsCerebellar CortexFemaleMaleMole RatsNerve Tissue ProteinsPhospholipase C betaPurkinje CellsNerve Tissue ProteinsPhospholipase C betazebrin II

Identifiers

PMID21298580
OpenAlexW1975708183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.