Trial reportEuropean journal of applied physiology2011
Three-month bilateral hopping intervention is ineffective in initiating bone biomarker response in healthy elderly men.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Non invasive techniques for direct muscle quality assessment after exercise intervention in older adults: a systematic review.BMC geriatrics · 2024Pooled it
- The Efficacy and Safety of Lower-Limb Plyometric Training in Older Adults: A Systematic Review.Sports medicine (Auckland, N.Z.) · 2019Pooled it
- High and odd impact exercise training improved physical function and fall risk factors in community-dwelling older men.Journal of musculoskeletal & neuronal interactions · 2018Trial
- Neuromuscular mechanics and hopping training in elderly.European journal of applied physiology · 2015Trial
- Effect of External Mechanical Stimuli on Human Bone: a narrative review.Progress in biomedical engineering (Bristol, England) · 2022Article
- Muscle and bone mass in middle-aged women: role of menopausal status and physical activity.Journal of cachexia, sarcopenia and muscle · 2020Article
- Predicting surface strains at the human distal radius during an in vivo loading task--finite element model validation and application.Journal of biomechanics · 2014Article
- Short-term jump activity on bone metabolism in female college-aged nonathletes.Journal of sports science & medicine · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In animal studies, bone adaptation has been initiated successfully without the transient force spike associated with high impact exercises. Consequently, a 12-week bilateral hopping on the balls of the feet intervention was conducted. 25 elderly men (age 72(SD4) years, height 171(6) cm, weight 75(9) kg) were randomly assigned into exercise and control groups. Ten subjects in each group completed the study. Carboxyterminal propeptide of type I collagen (CICP), bone-specific alkaline phosphatase (bALP) and carboxyterminal telopeptide of type I collagen (CTx) were measured from venous blood samples at baseline, at 2 weeks and at the end of the intervention. Maximal ground reaction force (GRF), osteogenic index (OI) and jump height (JH) were determined from bilateral hopping test and balance was assessed with velocity of center of pressure (COP(velocity)) while standing on the preferred leg with eyes open. The intervention consisted of 5-7 sets of 10 s timed bilateral hopping exercise at 75-90% intensity three times/week. There was no significant group × time interaction for GRF, OI and JH (P = 0.065). GRF (11% change from baseline vs. 4%), OI (15 vs. 6%) and COP(velocity) (-10 vs. -1%) were not influenced by the intervention (P > 0.170), while the control group improved JH (P = 0.031) (2 vs. 18%). For the biomarkers, no effect was observed in MANOVA (P = 0.536) or in univariate analyses (P = 0.082 to P = 0.820) (CICP -2 vs. -3%, CTx 8 vs. -12%, bALP 0 vs. -3.7%). Allowing transient impact force spikes may be necessary to initiate a bone response in elderly men as the intervention was ineffective.
Indexed as
Identifiers
21298444What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.