Trial reportEuropean journal of applied physiology2011
Nature of passive musculoarticular stiffness increase of ankle in female subjects with fibromyalgia syndrome.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02653807 (The Immediate Effects of Two Manual Therapy Techniques on Ankle Musculoarticular Stiffness and Dorsiflexion Range of Motion in People With Chronic Ankle Rigidity), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Immediate Effects of Two Manual Therapy Techniques on Ankle Musculoarticular Stiffness and Dorsiflexion Range of Motion in People With Chronic Ankle Rigidity: A Randomized Clinical Trial
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Mixed exercise training for adults with fibromyalgia.The Cochrane database of systematic reviews · 2019Pooled it
- Reevaluating fibromyalgia diagnosis: a proposal to integrate deep tendon reflex responses into current criteria.Rheumatology international · 2025Review
- Characterizing and Engineering Biomimetic Materials for Viscoelastic Mechanotransduction Studies.Tissue engineering. Part B, Reviews · 2022Review
- Effect of Age and Body Size on the Wrist's Viscoelasticity in Healthy Participants From 3 to 90 Years Old and Reliability Assessment.Frontiers in sports and active living · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to assess the passive elastic and viscous stiffness components of ankle in young, middle-aged and old adult female fibromyalgia subjects and compare the results with age-matched healthy control subjects. The passive musculoarticular stiffness of the ankles of 60 fibromyalgia subjects and 52 controls was quantified by measuring the ankle resistance to imposed sinusoidal rotary displacements at nine different oscillation frequencies. For each frequency, the resulting torque response of the ankles was decomposed into elastic and viscous components of the total stiffness. The self-perceived stiffness intensity of the ankles was assessed in fibromyalgia subjects by means of a visual analogue scale. Two-way ANOVA test indicated a significant effect of fibromyalgia (P < 0.001) and age (P < 0.001) on elastic stiffness results and a significant effect of age (P < 0.001) on viscous stiffness results. Post hoc Holm-Sidak test indicated that younger and middle-aged fibromyalgia subjects had a significant elastic stiffness increase of more than two times that of controls (P = 0.038 and P < 0.001, respectively). Middle-aged fibromyalgia subjects had a significant viscous stiffness increase of 1.2 times that of controls (P = 0.038). No significant differences in stiffness were observed between older fibromyalgia subjects and controls. In conclusion, the self-perceived stiffness increase of ankle reported by younger and middle-aged fibromyalgia subjects is due to changes in elastic and/or viscous musculoarticular structures around the ankle. The absence of changes in older fibromyalgia subjects is probably related to the ageing process of controls.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.