ReviewKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2011
Unload it: the key to the treatment of knee osteoarthritis.
Review in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04830748 (Effect of Mechanical Traction and Therapeutic Exercises in Treatment of Primary Knee Osteoarthritis), which is not on this map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Mechanical Traction and Therapeutic Exercises in Treatment of Primary Knee Osteoarthritis
Who cites it
39 citing papers in PubMed, 96 citations in OpenAlex.
- Lorecivivint, a Novel Intraarticular CDC-like Kinase 2 and Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A Inhibitor and Wnt Pathway Modulator for the Treatment of Knee Osteoarthritis: A Phase II Randomized Trial.Arthritis & rheumatology (Hoboken, N.J.) · 2020Trial
- Effects of Simulated Body-Mass Reduction on Peak Knee Joint Loads During Daily Functional Activities.Annals of biomedical engineering · 2026Article
- Article
- The dynamic 3D horse: analyzing the relationship between whole body pathomechanics and joint degeneration in the fetlocks.Frontiers in veterinary science · 2026Article
- The Effect of Thigh Muscle Forces on Knee Contact Force in Female Patients with Severe Knee Osteoarthritis.Bioengineering (Basel, Switzerland) · 2024Article
- Cartilage repair strategies in the knee according to Dutch Orthopedic Surgeons: a survey study.Archives of orthopaedic and trauma surgery · 2023Article
- Discharging the medial knee compartment: comparison of pressure distribution and kinematic shifting after implantation of an extra-capsular absorber system (ATLAS) and open-wedge high tibial osteotomy-a biomechanical in vitro analysis.Archives of orthopaedic and trauma surgery · 2023Article
- Article
- [Design and biomechanical analysis of a self-force source power-assisted knee orthotics actuated by liquid spring].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2022Article
- Patients with advanced lateral osteoarthritis can return to sports and work after distraction arthroplasty plus lateral meniscal allograft transplantation combined with cartilage repair.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Article
- The equine navicular apparatus as a premier enthesis organ: Functional implications.Veterinary surgery : VS · 2021Review
- Preliminary Evaluation of a New Orthotic for Patellofemoral and Multicompartment Knee Osteoarthritis.Rehabilitation research and practice · 2021Article
- Early-stage knee OA induced by MIA and MMT compared in the murine model via histological and topographical approaches.Scientific reports · 2020Article
- Biomechanical Study of a Tricompartmental Unloader Brace for Patellofemoral or Multicompartment Knee Osteoarthritis.Frontiers in bioengineering and biotechnology · 2020Article
- High tibial osteotomy increases patellofemoral pressure if adverted proximal, while open-wedge HTO with distal biplanar osteotomy discharges the patellofemoral joint: different open-wedge high tibial osteotomies compared to an extra-articular unloading device.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019Article
- Advances in modern osteotomies around the knee : Report on the Association of Sports Traumatology, Arthroscopy, Orthopaedic surgery, Rehabilitation (ASTAOR) Moscow International Osteotomy Congress 2017.Journal of experimental orthopaedics · 2019Review
- Joint distraction for knee osteoarthritis: protocol for a systematic review and meta-analysis.Systematic reviews · 2018Article
- Comparison of the efficiency of an extra-articular absorber system and high tibial osteotomy for unloading the medial knee compartment: an in vitro study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Article
- Is clinical measurement of anatomic axis of the femur adequate?Acta orthopaedica · 2017Article
- Long-term clinical benefit and cost-effectiveness of an 8-week multimodal knee osteoarthritis management program incorporating intra-articular sodium hyaluronate (HyalganJournal of pain research · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) of the knee is a major public health problem whose prevalence is expected to grow dramatically commensurate with the aging of the population and increasing rates of obesity. Unfortunately, little progress has been made therapeutically to avert this epidemic. We hypothesize that the lack of effective interventions is due, in large part, to an overemphasis on pharmacotherapy and direct chondral repair. Instead, we propose that research and development efforts be aimed at addressing the aberrant biomechanics that are the primary driver in the progression of knee OA. In particular, technologies that "unload" the joint may reverse the structural damage, which is the cardinal feature of this disease. Re-establishing a favorable local mechanical environment may not only delay the requirement for an invasive joint reconstruction procedure but obviate the need entirely.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.