ArticlePloS one2011
Reshaping of bulbar odor response by nasal flow rate in the rat.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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Who cites it
20 citing papers in PubMed, 38 citations in OpenAlex.
- Global coordination of brain activity by the breathing cycle.Nature reviews. Neuroscience · 2025Review
- Behavioral State-Dependent Modulation of Prefrontal Cortex Activity by Respiration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Temporal Relations between Cortical Network Oscillations and Breathing Frequency during REM Sleep.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- The deep and slow breathing characterizing rest favors brain respiratory-drive.Scientific reports · 2021Article
- Stimulus Driven Functional Transformations in the Early Olfactory System.Frontiers in cellular neuroscience · 2021Article
- Dynamic Impairment of Olfactory Behavior and Signaling Mediated by an Olfactory Corticofugal System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020Article
- Input dependent modulation of olfactory bulb activity by HDB GABAergic projections.Scientific reports · 2020Article
- Article
- Inhalation Frequency Controls Reformatting of Mitral/Tufted Cell Odor Representations in the Olfactory Bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Comparison of realistic and idealized breathing patterns in computational models of airflow and vapor dosimetry in the rodent upper respiratory tract.Inhalation toxicology · 2016Article
- Cholinergic inputs from Basal forebrain add an excitatory bias to odor coding in the olfactory bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- The olfactory bulb theta rhythm follows all frequencies of diaphragmatic respiration in the freely behaving rat.Frontiers in behavioral neuroscience · 2014Article
- Beta and gamma oscillatory activities associated with olfactory memory tasks: different rhythms for different functional networks?Frontiers in behavioral neuroscience · 2014Review
- Two distinct olfactory bulb sublaminar networks involved in gamma and beta oscillation generation: a CSD study in the anesthetized rat.Frontiers in neural circuits · 2014Article
- Testing the sorption hypothesis in olfaction: a limited role for sniff strength in shaping primary odor representations during behavior.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Respiration drives network activity and modulates synaptic and circuit processing of lateral inhibition in the olfactory bulb.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Article
- Faster, deeper, better: the impact of sniffing modulation on bulbar olfactory processing.PloS one · 2012Article
- The RUB Cage: Respiration-Ultrasonic Vocalizations-Behavior Acquisition Setup for Assessing Emotional Memory in Rats.Frontiers in behavioral neuroscience · 2011Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe impact of respiratory dynamics on odor response has been poorly studied at the olfactory bulb level. However, it has been shown that sniffing in the behaving rodent is highly dynamic and varies both in frequency and flow rate. Bulbar odor response could vary with these sniffing parameter variations. Consequently, it is necessary to understand how nasal airflow can modify and shape odor response at the olfactory bulb level. METHODOLOGY AND PRINCIPAL
findingsTo assess this question, we used a double cannulation and simulated nasal airflow protocol on anesthetized rats to uncouple nasal airflow from animal respiration. Both mitral/tufted cell extracellular unit activity and local field potentials (LFPs) were recorded. We found that airflow changes in the normal range were sufficient to substantially reorganize the response of the olfactory bulb. In particular, cellular odor-evoked activities, LFP oscillations and spike phase-locking to LFPs were strongly modified by nasal flow rate.
conclusionOur results indicate the importance of reconsidering the notion of odor coding as odor response at the bulbar level is ceaselessly modified by respiratory dynamics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.