ReviewCurrent opinion in obstetrics & gynecology2011
Evolving applications of microarray analysis in prenatal diagnosis.
Review in Current opinion in obstetrics & gynecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- An economic analysis of prenatal cytogenetic technologies for sonographically detected fetal anomalies.American journal of medical genetics. Part A · 2014Pooled it
- How to choose a test for prenatal genetic diagnosis: a practical overview.American journal of obstetrics and gynecology · 2023Article
- Implications of Using Host Response-Based Molecular Diagnostics on the Management of Bacterial and Viral Infections: A Review.Frontiers in medicine · 2022Review
- Review
- Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations.Human cell · 2020Article
- Chromosomal microarray vs. NIPS: analysis of 5541 low-risk pregnancies.Genetics in medicine : official journal of the American College of Medical Genetics · 2019Article
- Opening Pandora's box?: ethical issues in prenatal whole genome and exome sequencing.Prenatal diagnosis · 2018Review
- What women want: lead considerations for current and future applications of noninvasive prenatal testing in prenatal care.Birth (Berkeley, Calif.) · 2014Article
- Microarrays as a diagnostic tool in prenatal screening strategies: ethical reflection.Human genetics · 2014Article
- Detection of chromosomal breakpoints in patients with developmental delay and speech disorders.PloS one · 2014Article
- 22q11.2 deletions in patients with conotruncal defects: data from 1,610 consecutive cases.Pediatric cardiology · 2013Article
- Women's experiences receiving abnormal prenatal chromosomal microarray testing results.Genetics in medicine : official journal of the American College of Medical Genetics · 2013Article
- The scope of prenatal diagnosis for women at increased risk for aneuploidies: views and preferences of professionals and potential users.Journal of community genetics · 2013Article
- Clinical impact of copy number variation analysis using high-resolution microarray technologies: advantages, limitations and concerns.Genome medicine · 2012Review
- Advances in prenatal screening: the ethical dimension.Nature reviews. Genetics · 2011Review
- Constitutional Ring Chromosomes in Greek Pediatric Patients: A 50-year Single-center Cytogenetic Study.In vivo (Athens, Greece)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purpose of reviewEvaluation of copy number variation by microarray analysis has significant advantages over standard metaphase karyotyping and is quickly becoming the primary means of postnatal genetic evaluation for neonates and infants with dysmorphic features or cognitive difficulties. Before this technology is routinely used for prenatal diagnosis, further evaluation of its value and the clinical dilemmas it may introduce requires further study. This article reviews the recent literature on array technology use in prenatal diagnosis. RECENT
findingsThe use of microarray analysis for routine prenatal diagnosis is still being investigated. Use in certain prenatal situations such as the fetus with structural anomalies or those who are stillborn appears to add important, clinically relevant information. There are a broad range of array designs available and recent research has focused on the appropriate design for prenatal testing. Patient counseling may occasionally be difficult because of the uncertain phenotype associated with some array findings. SUMMARY: We present a brief overview of microarray technology including benefits and limitations. Previous research regarding use of microarray in prenatal diagnosis including specific scenarios of anomalous fetuses and abnormal karyotype is reviewed. Current guidelines and the authors' recommendations are presented.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.