Evidence map›Paper›PMID 21297468›Full record

ReviewCurrent opinion in endocrinology, diabetes, and obesity2011

Hypoglycemia complicating bariatric surgery: incidence and mechanisms.

Karen E Foster-Schubert

Abstract readReview
In one paragraph

Review in Current opinion in endocrinology, diabetes, and obesity, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Effect of alcohol ingestion on plasma glucose kinetics after Roux-en-Y gastric bypass surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
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  11. [Conversional and endoscopic procedures following bariatric surgery].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016
    Review
  12. Article
  13. Article
  14. Post-Gastric Bypass Hypoglycemia.Current diabetes reports · 2016
    Review
  15. FROM COMPLEX EVOLVING TO SIMPLE: CURRENT REVISIONAL AND ENDOSCOPIC PROCEDURES FOLLOWING BARIATRIC SURGERY.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2016
    Article
  16. Article
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  18. The Diagnosis and Management of Hyperinsulinaemic Hypoglycaemia.Journal of clinical research in pediatric endocrinology · 2015
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Karen E Foster-SchubertDivision of Metabolism, Endocrinology and Nutrition, Department of Medicine, University of Washington, V.A. Puget Sound Healthcare System, Seattle, Washington 98108, USA. kfoster@u.washington.edu

Funding

Feasibility, Efficacy, and Mechanisms of Surgical vs Medical Diabetes TreatmentR01DK089528 · NIDDK · UNIVERSITY OF WASHINGTON · PI CUMMINGS, DAVID EUSTACE, FLUM, DAVID R · 2010 to 2012
$1.7M
HEPATOCYTE GROWTH AND DIFFERENTIATION IN VITROF32DK008952 · NIDDK · HOWARD UNIVERSITY · PI HAMILTON-AUGUSTUS, YOLANDA L · 1994 to 1995
–
NIDDK NIH HHS F32 DK008952NIDDK NIH HHS R01 DK08952NIDDK NIH HHS R01 DK089528NIDDK NIH HHS R01 DK517498
6 · The paper itself

Abstract

purpose of reviewTo discuss the clinical scope and frequency of hypoglycemia following bariatric surgery, and possible mechanisms mediating this potentially life-threatening complication. RECENT

findingsConsequent to the rise in severe obesity, bariatric surgery is being performed with ever increasing frequency. Although data continue to accumulate supporting the myriad metabolic and other health benefits of bariatric surgery, there are also concerns regarding the mounting reports of severe hypoglycemia. The problem is particularly significant following gastric bypass, with the first concerns raised in 2005 following a case series reported from the Mayo Clinic. A Swedish nationwide cohort study recently estimated the frequency of this complication suggesting it was less than 1%. Hypotheses regarding the mechanism(s) by which hypoglycemia arise following gastric bypass range from beta cell expansion to altered beta cell function as well as nonbeta cell factors. SUMMARY: Regardless of the incidence, the severity of hypoglycemia for select patients following gastric bypass necessitates that we strive to gain a better understanding of the underlying mechanisms. With such knowledge, those patients at greater risk for this complication might be identified preoperatively, and decisions regarding their surgical management optimized to reduce this risk.

Indexed as

Bariatric SurgeryHumansHypoglycemiaIncidencePatient SelectionRisk AssessmentRisk FactorsSeverity of Illness IndexTreatment Outcome

Identifiers

PMID21297468
PMCPMC3190577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.