ArticleThe Plant cell2011
An Arabidopsis dual-localized pentatricopeptide repeat protein interacts with nuclear proteins involved in gene expression regulation.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed, 110 citations in OpenAlex.
- CmPPR4 gene controls drought resilience in melon ecotypes.Plant biotechnology journal · 2025Article
- Transcriptomic Analysis to Understand the Nitrogen Stress Response Mechanism in BNI-Enabled Wheat.International journal of molecular sciences · 2025Article
- Pentatricopeptide repeat proteins in plants: Cellular functions, action mechanisms, and potential applications.Plant communications · 2025Review
- Comprehensive Analysis of theInternational journal of molecular sciences · 2024Article
- Transcriptome-wide Identification of Nine Tandem Repeat Protein Families in Roselle (Tropical life sciences research · 2024Article
- Chloroplast C-to-U editing, regulated by a PPR protein BoYgl-2, is important for chlorophyll biosynthesis in cabbage.Horticulture research · 2024Article
- Unveiling orphan receptor-like kinases in plants: novel client discovery using high-confidence library predictions in the Kinase-Client (KiC) assay.Frontiers in plant science · 2024Article
- Species-specific effects of production practices on genetic diversity in plant reintroduction programs.Evolutionary applications · 2023Article
- Genome-Wide Analysis of TCP Transcription Factors and Their Expression Pattern Analysis of Rose Plants (Current issues in molecular biology · 2023Article
- Physiological Roles and Mechanisms of Action of Class I TCP Transcription Factors.International journal of molecular sciences · 2023Review
- The PPR-Domain Protein SOAR1 Regulates Salt Tolerance in Rice.Rice (New York, N.Y.) · 2022Article
- Identification and expression analysis of the grape pentatricopeptide repeat (PPR) gene family in abiotic stress.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022Article
- Maize PPR278 Functions in Mitochondrial RNA Splicing and Editing.International journal of molecular sciences · 2022Article
- Genome-Wide Identification and Transcript Analysis of TCP Gene Family in Banana (Musa acuminata L.).Biochemical genetics · 2022Article
- PPR647 Protein Is Required for Chloroplast RNA Editing, Splicing and Chloroplast Development in Maize.International journal of molecular sciences · 2021Article
- Physiological and Proteomic Analyses of Different Ecotypes of Reed (Frontiers in plant science · 2021Article
- Genome communication in plants mediated by organelle-n-ucleus-located proteins.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Review
- The Mitochondrial Pentatricopeptide Repeat Protein PPR18 Is Required for theInternational journal of molecular sciences · 2020Article
- Mitochondrial Pentatricopeptide Repeat Protein, EMB2794, Plays a Pivotal Role in NADH Dehydrogenase Subunit nad2 mRNA Maturation in Arabidopsis thaliana.Plant & cell physiology · 2020Article
- Two Pentatricopeptide Repeat Proteins Are Required for the Splicing ofFrontiers in plant science · 2020Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following the endosymbiotic acquisition of mitochondria by eukaryotic cells, most of the genes in this organelle were transferred to the nucleus. To maintain mitochondrial biogenesis and function, nuclear and mitochondrial genomes require regulated and coordinated expression. In plant organelles, nuclear-encoded proteins targeted to the organelles control posttranscriptional and posttranslational mechanisms. Pentatricopeptide repeat (PPR) proteins are good candidates to play such regulatory roles. Here, we identify PNM1 (for PPR protein localized to the nucleus and mitochondria 1), a novel PPR protein that is dual localized to mitochondria and nuclei in Arabidopsis thaliana, as observed by green fluorescent protein fusions and immunodetection on subcellular fractions and on histological sections. Genetic complementation showed that loss of PNM1 function in mitochondria, but not in nuclei, is lethal for the embryo. In mitochondria, it is associated with polysomes and may play a role in translation. A genetic screen in yeast identified protein partners of PNM1. These partners, the nucleosome assembly protein NAP1, and the transcription factor TCP8 interact with PNM1 in the nucleus in planta. Furthermore, TCP8 can bind the promoter of PNM1. This suggests that PNM1 might be involved in the regulation of its own gene expression in the nucleus and could thus play a role in gene expression adjustments between mitochondria and the nucleus.
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