ArticleThe American journal of medicine2011
Marked reduction in 30-day mortality among elderly patients with community-acquired pneumonia.
Article in The American journal of medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Changes in hospital mortality for United States intensive care unit admissions from 1988 to 2012.Critical care (London, England) · 2013Trial
- Demographic and geographic hotspots of Alzheimer's disease and pneumonia-related mortality among older adults in the United States: a retrospective analysis.European journal of medical research · 2026Article
- Unveiling etiology and mortality risks in community-acquired pneumonia: A machine learning approach.Biomolecules & biomedicine · 2025Article
- Observational
- Can Electronic Decision Support Tools Really Reduce Mortality from Community-acquired Pneumonia?American journal of respiratory and critical care medicine · 2022Article
- The hospitalization burden of all-cause pneumonia in China: A population-based study, 2009-2017.The Lancet regional health. Western Pacific · 2022Article
- Article
- Simulated Adoption of 2019 Community-Acquired Pneumonia Guidelines Across 114 Veterans Affairs Medical Centers: Estimated Impact on Culturing and Antibiotic Selection in Hospitalized Patients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- The Relative Ability of Comorbidity Ascertainment Methodologies to Predict In-Hospital Mortality Among Hospitalized Community-acquired Pneumonia Patients.Medical care · 2018Observational
- Trends in mortality from pneumonia in the Europe union: a temporal analysis of the European detailed mortality database between 2001 and 2014.Respiratory research · 2018Article
- Article
- Factors associated with 30-day mortality in elderly inpatients with community acquired pneumonia during 2 influenza seasons.Human vaccines & immunotherapeutics · 2017Article
- Article
- Trends in Antibiotic Use and Nosocomial Pathogens in Hospitalized Veterans With Pneumonia at 128 Medical Centers, 2006-2010.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015Article
- Can we make performance measures more resilient to the effects of coding?Critical care medicine · 2015Article
- Cardiotoxicity during invasive pneumococcal disease.American journal of respiratory and critical care medicine · 2015Review
- Lower mortality rate in elderly patients with community-onset pneumonia on treatment with aspirin.Journal of the American Heart Association · 2015Article
- Validation of an administrative claims-based diagnostic code for pneumonia in a US-based commercially insured COPD population.International journal of chronic obstructive pulmonary disease · 2015Article
- Trends in the leading causes of death in Korea, 1983-2012.Journal of Korean medical science · 2014Article
- National patterns of risk-standardized mortality and readmission after hospitalization for acute myocardial infarction, heart failure, and pneumonia: update on publicly reported outcomes measures based on the 2013 release.Journal of general internal medicine · 2014Article
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4 authors.
Funding
Abstract
backgroundCommunity-acquired pneumonia is the most common infectious cause of death in the US. Over the last 2 decades, patient characteristics and clinical care have changed. To understand the impact of these changes, we quantified incidence and mortality trends among elderly adults.
methodsWe used Medicare claims to identify episodes of pneumonia, based on a validated combination of diagnosis codes. Comorbidities were ascertained using the diagnosis codes located on a 1-year look back. Trends in patient characteristics and site of care were compared. The association between year of pneumonia episode and 30-day mortality was then evaluated by logistic regression, with adjustment for age, sex, and comorbidities.
resultsWe identified 2,654,955 cases of pneumonia from 1987-2005. During this period, the proportion treated as inpatients decreased, the proportion aged ≥80 years increased, and the frequency of many comorbidities rose. Adjusted incidence increased to 3096 episodes per 100,000 population in 1999, with some decrease thereafter. Age/sex-adjusted mortality decreased from 13.5% to 9.7%, a relative reduction of 28.1%. Compared with 1987, the risk of mortality decreased through 2005 (adjusted odds ratio, 0.46; 95% confidence interval, 0.44-0.47). This result was robust to a restriction on comorbid diagnoses assessing for the results' sensitivity to increased coding.
conclusionsThese findings show a marked mortality reduction over time in community-acquired pneumonia patients. We hypothesize that increased pneumococcal and influenza vaccination rates as well as wider use of guideline-concordant antibiotics explain a large portion of this trend.
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