Evidence map›Paper›PMID 21294513›Full record

ArticleJournal of the American Chemical Society2011

Development and applications of fluorogenic probes for mercury(II) based on vinyl ether oxymercuration.

Shin Ando, Kazunori Koide

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. HgSensors (Basel, Switzerland) · 2019
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Shin AndoDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
Kazunori Koide

Funding

Chemical Approaches for the Discovery of New Cancer Therapeutic TargetsR01CA120792 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KOIDE, KAZUNORI · 2006 to 2009
$755k
NCI NIH HHS R01 CA120792NCI NIH HHS R01CA120792
6 · The paper itself

Abstract

Mercury is a major threat to the environment and to human health. It is highly desirable to develop a user-friendly kit for on-site mercury detection. Such a method must be able to detect mercury below the threshold levels for drinking water, 1-2 ppb. We developed a fluorescence method based on the oxymercuration of vinyl ethers to detect mercury in dental and environmental samples. Chloride ions interfered with the oxymercuration reaction, but the addition of AgNO(3) solved this problem. Fine electronic and structural tuning led to the development of a more responsive probe that was less sensitive to chloride ion interference. This second-generation probe could detect 1 ppb mercury ions in water.

Indexed as

EthersFluorescent DyesMercuryMolecular StructureStereoisomerismVinyl CompoundsEthersFluorescent DyesMercuryVinyl Compounds

Identifiers

PMID21294513
PMCPMC3045475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.