Trial reportThe Pan African medical journal2010
Regular vitamin C supplementation during pregnancy reduces hospitalization: outcomes of a Ugandan rural cohort study.
Trial report in The Pan African medical journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Global Prevalence of Anemia in Pregnant Women: A Comprehensive Systematic Review and Meta-Analysis.Maternal and child health journal · 2022Pooled it
- Vitamin supplementation for preventing miscarriage.The Cochrane database of systematic reviews · 2016Pooled it
- Vitamin C supplementation in pregnancy.The Cochrane database of systematic reviews · 2015Pooled it
- Association between the Dietary Inflammatory Index and the Risk of Cesarean Delivery.Iranian journal of public health · 2024Article
- Ascorbic acid intake during pregnancy.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023Review
- Evidence based recommendations for an optimal prenatal supplement for women in the US: vitamins and related nutrients.Maternal health, neonatology and perinatology · 2022Review
- Association between antioxidant vitamins and oxidative stress among patients with a complete hydatidiform mole.Clinics (Sao Paulo, Brazil) · 2020Observational
- Prevalence and associated factors of anemia among pregnant women of Mekelle town: a cross sectional study.BMC research notes · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin C or ascorbic acid is a hydro-soluble lactone (synthesized from glucose) essential to human body and available from diet. Despite its broad availability in fruits and vegetables, in many developing countries the incidence of clinical symptoms due to the vitamin deficiency is still very high. Also, pregnant women in the developing countries are frequently hospitalized for several preventable reasons such as anemia in pregnancy, mostly iron-deficient anemia (IDA) and the upper/lower respiratory tract infections (RTI). The aim of the study was to investigate, in a Ugandan rural pregnant women cohort, the preventive effects of vitamin C supplementation on hospital admission.
methods384 pregnant women met the inclusion criteria and were randomly assigned to receive either 400 mg of vitamin C daily (187) or not (197) in addition to their standard antenatal vitamins until delivery. The primary outcome measure of this study was to assess the prevention of hospitalization during pregnancy in the group of women supplemented with vitamin C compared to the controls. Fisher's exact test was employed in this assessment.
results42.2% women in the vitamin C group and 27.9% in the control group were not hospitalized during pregnancy; this difference was found statistically significant.
conclusionThe results of this study suggest including vitamin C in the guidelines of multivitamin prevention for pregnant women, especially in developing countries where seasonal availability of fruits and vegetables could result in adverse clinical outcomes.
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