ArticleAmerican journal of nephrology2011
Racial and ethnic differences in mortality of hemodialysis patients: role of dietary and nutritional status and inflammation.
Article in American journal of nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01415570 (Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease), which is not on this map. Cited by 44 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease (CKD) - A Prospective Data Collection Study
Who cites it
44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Estimating the association between systemic Interleukin-6 and mortality in the dialysis population. Re-analysis of the global fluid study, systematic review and meta-analysis.BMC nephrology · 2023Pooled it
- Interleukin-6 levels can be used to estimate cardiovascular and all-cause mortality risk in dialysis patients: A meta-analysis and a systematic review.Immunity, inflammation and disease · 2023Pooled it
- A comprehensive exploration of chronic kidney disease and dialysis in Canada's Indigenous population: from epidemiology to genetic influences.International urology and nephrology · 2024Review
- The epidemiology and microbiology of central venous catheter related bloodstream infections among hemodialysis patients in the Philippines: a retrospective cohort study.BMC nephrology · 2024Article
- Data-driven, two-stage machine learning algorithm-based prediction scheme for assessing 1-year and 3-year mortality risk in chronic hemodialysis patients.Scientific reports · 2023Observational
- Study on the correlation between bioelectrical impedance analysis index and protein energy consumption in maintenance dialysis patients.Nutrition journal · 2023Article
- Blood Levels of Endocannabinoids, Oxylipins, and Metabolites Are Altered in Hemodialysis Patients.International journal of molecular sciences · 2022Article
- Comorbidity burden may explain adiponectin's paradox as a marker of increased mortality risk in hemodialysis patients.Scientific reports · 2021Article
- Survival of the Fittest: Addressing the Disparities in the Burden of Chronic Kidney Disease.Cureus · 2020Review
- Racial differences in inflammation and outcomes of aging among kidney transplant candidates.BMC nephrology · 2019Article
- Survival predictors in anuric patients on peritoneal dialysis: A prospective, multicenter, propensity score-matched cohort study.PloS one · 2018Article
- Changes in urine volume and serum albumin in incident hemodialysis patients.Hemodialysis international. International Symposium on Home Hemodialysis · 2017Article
- Nutritional status after conversion from conventional to in-centre nocturnal hemodialysis.International urology and nephrology · 2017Article
- Association of Growth Differentiation Factor 15 with Mortality in a Prospective Hemodialysis Cohort.Cardiorenal medicine · 2017Article
- Concurrence of Serum Creatinine and Albumin With Lower Risk for Death in Twice-Weekly Hemodialysis Patients.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2017Article
- Racial Differences in Survival of Incident Home Hemodialysis and Kidney Transplant Patients.Transplantation · 2016Article
- Low prealbumin levels are independently associated with higher mortality in patients on peritoneal dialysis.Kidney research and clinical practice · 2016Article
- Why minorities live longer on dialysis: an in-depth examination of the Danish nephrology registry.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2016Article
- Lean Body Mass and Survival in Hemodialysis Patients and the Roles of Race and Ethnicity.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2016Article
- Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
Abstract
backgroundRacial/ethnic disparities prevail among hemodialysis patients. We hypothesized that significant differences exist between Black and non-Hispanic and Hispanic White hemodialysis patients in nutritional status, dietary intake and inflammation, and that they account for racial survival disparities.
methodsIn a 6-year (2001-2007) cohort of 799 hemodialysis patients, we compared diet and surrogates of nutritional-inflammatory status and their mortality-predictabilities between 279 Blacks and 520 Whites using matched and regression analyses and Cox with cubic splines.
resultsIn age-, gender- and diabetes-matched analyses, Blacks had higher lean body mass and serum prealbumin, creatinine and homocysteine levels than Whites. In case-mix-adjusted analyses, dietary intakes in Blacks versus Whites were higher in energy (+293 ± 119 cal/day) and fat (+18 ± 5 g/day), but lower in fiber (-2.9 ± 1.3 g/day) than Whites. In both races, higher serum albumin, prealbumin and creatinine were associated with greater survival, whereas CRP and IL-6, but not TNF-α, were associated with increased mortality. The highest (vs. lowest) quartile of IL-6 was associated with a 2.4-fold (95% CI: 1.3-3.8) and 4.1-fold (2.2-7.2) higher death risk in Blacks and Whites, respectively.
conclusionsSignificant racial disparities exist in dietary, nutritional and inflammatory measures, which may contribute to hemodialysis outcome disparities. Testing race-specific dietary and/or anti-inflammatory interventions is indicated.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.