ArticleJournal of epidemiology2011
Attributable fractions of risk factors for cardiovascular diseases.
Article in Journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Association of Coronary Artery Calcification with Estimated Coronary Heart Disease Risk from Prediction Models in a Community-Based Sample of Japanese Men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA).Journal of atherosclerosis and thrombosis · 2018Trial
- Global burden of ischemic heart disease from 1990 to 2021: Findings from the Global Burden of Disease Study 2021 and predictions to 2030.Chinese medical journal · 2026Article
- Article
- Individual Differences in the Association of Lifestyle with Cardiometabolic Risk in Middle-Aged Koreans Based on Traditional Korean Medicine.International journal of environmental research and public health · 2022Article
- Possible burden of hyperuricaemia on mortality in a community-based population: a large-scale cohort study.Scientific reports · 2021Article
- Attributable Fractions of Nonalcoholic Fatty Liver Disease for Mortality in the United States: Results From the Third National Health and Nutrition Examination Survey With 27 Years of Follow-up.Hepatology (Baltimore, Md.) · 2020Article
- Impact of a structured yoga program on blood pressure reduction among hypertensive patients: study protocol for a pragmatic randomized multicenter trial in primary health care settings in Nepal.BMC complementary and alternative medicine · 2018Article
- Stem cell therapy in intracerebral hemorrhage rat model.World journal of stem cells · 2015Review
- A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2015Article
- The impact of cigarette smoking on 24-hour blood pressure, inflammatory and hemostatic activity, and cardiovascular risk in Japanese hypertensive patients.Journal of clinical hypertension (Greenwich, Conn.) · 2013Article
- Adult mortality attributable to preventable risk factors for non-communicable diseases and injuries in Japan: a comparative risk assessment.PLoS medicine · 2012Article
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1 author.
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Abstract
backgroundCardiovascular disease (CVD) is a leading cause of death in Japan. To reduce the threat of CVD, it is important to identify its major risk factors. The population attributable fraction (PAF) is calculated from the prevalence and relative risk of risk factors and can be used to estimate the burden of these factors with respect to CVD. We analyzed the findings from several prospective studies to determine the PAFs of CVD.
methodsPAF was calculated as pd × (multiadjusted relative risk - 1)/multiadjusted relative risk, where pd is the proportion of patients exposed to that risk factor category, according to data from the Ohsaki Cohort Study, EPOCH-JAPAN, NIPPON DATA80, Miyagi Cohort Study, CARDIA Study, and ARIC Study.
resultsNonoptimal blood pressure explained 47% and 26% of CVD mortality in middle-aged and elderly Japanese, respectively. Cigarette smoking explained 34% of all-cause mortality in middle-aged men. The combination of hypertension and cigarette smoking explained 57% and 44% of CVD mortality in younger men and women, respectively. Furthermore, the presence of at least 1 nonoptimal risk factor explained most CVD deaths and all-cause deaths.
conclusionsEstablished CVD risk factors, especially high blood pressure and cigarette smoking, explained a large proportion of CVD mortality and all-cause mortality. Prevention, early detection, and treatment of these conventional risk factors are required to reduce mortality risk.
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