Evidence map›Paper›PMID 21292885›Full record

ArticleThe American journal of tropical medicine and hygiene2011

Economic impact of dengue illness in the Americas.

Donald S Shepard, Laurent Coudeville, Yara A Halasa, Betzana Zambrano, Gustavo H Dayan

2 registry-linked trialsAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 192 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03055585 naterminatednot on this mapstarted 2017, after this paper: background citation

Applying Wolbachia to Eliminate Dengue (AWED): A Non-blinded Cluster Randomised Controlled Trial to Assess the Efficacy of Wolbachia-infected Mosquito Deployments to Reduce Dengue Incidence in Yogyakarta, Indonesia

TypeinterventionalSponsorGadjah Mada UniversityRan2017 to 2020Enrolled8,173ConditionsDengue, Zika Virus Infection, Chikungunya FeverArmsWolbachia-infected Aedes aegypti mosquitoes, standard practice dengue control
NCT03631719 completednot on this mapstarted 2017, after this paper: background citation

World Mosquito Program - Colombia (WMP-COLOMBIA): The Impact of City-wide Deployment of Wolbachia-infected Mosquitoes on Arboviral Disease Incidence in Medellin and Bello, Colombia

Typeobservational_patient_registrySponsorUniversidad de AntioquiaRan2017 to 2021Enrolled834ConditionsDengue, Chikungunya Virus Infection, Zika Virus InfectionArmsWolbachia-carrying Ae.aegypti mosquitoes
3 · Its place in the literature

Who cites it

192 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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  7. Economic and disease burden of dengue in Southeast Asia.PLoS neglected tropical diseases · 2013
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  15. Review
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  18. Mechanistic Modeling ofGeoHealth · 2025
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132 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Donald S ShepardBrandeis University, Waltham, MA 02454-9110, USA. shepard@brandeis.edu
Laurent Coudeville
Yara A Halasa
Betzana Zambrano
Gustavo H Dayan

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The growing burden of dengue in endemic countries and outbreaks in previously unaffected countries stress the need to assess the economic impact of this disease. This paper synthesizes existing studies to calculate the economic burden of dengue illness in the Americas from a societal perspective. Major data sources include national case reporting data from 2000 to 2007, prospective cost of illness studies, and analyses quantifying underreporting in national routine surveillance systems. Dengue illness in the Americas was estimated to cost $2.1 billion per year on average (in 2010 US dollars), with a range of $1-4 billion in sensitivity analyses and substantial year to year variation. The results highlight the substantial economic burden from dengue in the Americas. The burden for dengue exceeds that from other viral illnesses, such as human papillomavirus (HPV) or rotavirus. Because this study does not include some components (e.g., vector control), it may still underestimate total economic consequences of dengue.

Indexed as

Caribbean RegionCentral AmericaCost of IllnessDengueHealth Care CostsHumansSouth America

Identifiers

PMID21292885
PMCPMC3029168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.