ReviewJournal of the American College of Cardiology2011
Clinical, molecular, and genomic changes in response to a left ventricular assist device.
Review in Journal of the American College of Cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
47 citing papers in PubMed.
- Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution.Basic research in cardiology · 2016Trial
- Mesenchymal precursor cells as adjunctive therapy in recipients of contemporary left ventricular assist devices.Circulation · 2014Trial
- Mitochondrial and Cardiolipin Adaptations to Ventricular Assist Device Support in Pediatric Versus Adult Failing Myocardium.bioRxiv : the preprint server for biology · 2026Article
- Mechanisms and Therapeutic Potential of Human Cardiomyocyte Proliferation.Journal of cardiovascular development and disease · 2026Review
- Predictors of long-term success after successful explantation of continuous flow left ventricular assist device support.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Case Report: Unmasking sustainable left ventricular recovery in chronic heart failure with axillary temporary mechanical circulatory support.Frontiers in cardiovascular medicine · 2024Article
- Early reverse remodeling of left heart morphology and function evaluated by cardiac magnetic resonance in hypertrophic obstructive cardiomyopathy after transapical beating-heart septal myectomy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Article
- Left ventricular assist device explantation using a new double-patch technique†.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Article
- Percutaneous Decommissioning 11 Years After Initial CF-LVAD Placement.JACC. Case reports · 2022Article
- Myocardial recovery evaluation from ventricular assist device in patients with dilated cardiomyopathy.ESC heart failure · 2022Article
- Ventricular assist device-promoted recovery and technical aspects of explant.JTCVS techniques · 2021Article
- Weaning from ventricular assist device support after recovery from left ventricular failure with or without secondary right ventricular failure.Cardiovascular diagnosis and therapy · 2021Review
- Characterization of left ventricular myocardial sodium-glucose cotransporter 1 expression in patients with end-stage heart failure.Cardiovascular diabetology · 2020Article
- Expanding the Scope of Multimodality Imaging in Durable Mechanical Circulatory Support.JACC. Cardiovascular imaging · 2020Review
- Characteristics of Blood Metabolic Profile in Coronary Heart Disease, Dilated Cardiomyopathy and Valvular Heart Disease Induced Heart Failure.Frontiers in cardiovascular medicine · 2020Article
- Can stem cell therapy increase the rate of myocardial recovery in left ventricular assist device-supported advanced heart failure patients?-current data and future perspectives.Annals of translational medicine · 2019Article
- Characterization of biventricular alterations in myocardial (reverse) remodelling in aortic banding-induced chronic pressure overload.Scientific reports · 2019Article
- Pulmonary function assessment post-left ventricular assist device implantation.ESC heart failure · 2019Article
- A new tool for an explantation strategy of HeartMate 3™ left ventricular assist device.Journal of thoracic disease · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
The use of left ventricular assist devices in treating patients with end-stage heart failure has increased significantly in recent years, both as a bridge to transplantation and as destination therapy in those who are ineligible for cardiac transplantation. This increase is based largely on the results of several recently completed clinical trials with the new second-generation continuous-flow devices that showed significant improvements in survival, functional capacity, and quality of life. Additional information on the use of the first- and second-generation left ventricular assist devices has come from a recently released report spanning the years 2006 to 2009, from the Interagency Registry for Mechanically Assisted Circulatory Support, a National Heart, Lung, and Blood Institute-sponsored collaboration between the U.S. Food and Drug Administration, the Centers for Medicare and Medicaid Services, and the scientific community. The authors review the latest clinical trials and data from the registry, with tight integration of the landmark molecular, cellular, and genomic research that accompanies the reverse remodeling of the human heart in response to a left ventricular assist device and functional recovery that has been reported in a subset of these patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.