Evidence map›Paper›PMID 21291960›Full record

ReviewBiochimica et biophysica acta2011

Viruses and asthma.

Daniel E Dulek, R Stokes Peebles

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 56 citations in OpenAlex.

  1. Trial
  2. Beyond respiratory syncytial virus and rhinovirus: The other viral respiratory bandits.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
  3. Indoor bioaerosols and asthma: Overview, implications, and mitigation strategies.The Journal of allergy and clinical immunology · 2025
    Review
  4. Article
  5. Review
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Genetic Signatures of Asthma Exacerbation.Allergy, asthma & immunology research · 2017
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Group 2 innate lymphoid cells: new players in human allergic diseases.Journal of investigational allergology & clinical immunology · 2015
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Daniel E DulekDepartment of Pediatrics, Division of Pediatric Infectious Diseases, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, TN 37232-2650, USA. daniel.dulek@vanderbilt.edu
R Stokes Peebles
Monroe Carell Jr. Children's Hospital · USVanderbilt University · US

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
Viral and Host Determinants of Infant and Childhood Allergy and AsthmaU19AI095227 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Dawn C Newcomb · 2011 to 2026
$34.9M
THE PHARMACOLOGY OF INHIBITORS OF HEME PROTEIN-CATALYZED LIPID PEROXIDATIONP50GM015431 · NIGMS · VANDERBILT UNIVERSITY · PI MARNETT, LAWRENCE J. · 1985 to 2010
$15.0M
Therapeutic Modulation of Endothelial Cell TetrahydrobiopterinP01GM015431 · NIGMS · VANDERBILT UNIVERSITY · PI ROBERTS, II, L JACKSON · 2011 to 2015
$9.5M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) KL2KL2RR024977 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$3.0M
The Role of PGI2 in Allergic InflammationR01HL090664 · NHLBI · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 2009 to 2013
$1.9M
The Role of IL-17 in RSV-induced Mucus and Airway ResponsivenessR01AI070672 · NIAID · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 2007 to 2011
$1.9M
The Structure and Function of the CRTH2 PDG2 ReceptorR01AI059108 · NIAID · VANDERBILT UNIVERSITY · PI BREYER, RICHARD M. · 2005 to 2009
$1.8M
The Vanderbilt Institute for Clinical and Translational Research (VICTR) TL1TL1RR024978 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$1.3M
The Role of Il-13 in Regulating Th17 Cytokine ProductionR21HL106446 · NHLBI · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 2011 to 2012
$439k
The role of cyclooxygenase in the adaptive immune response and toleranceI01BX000624 · VA · VETERANS HEALTH ADMINISTRATION · PI PEEBLES, RAY STOKES · 2009 to 2019
–
BLRD VA I01 BX000624NCRR NIH HHS KL2 RR024977NCRR NIH HHS TL1 RR024978NCRR NIH HHS UL1 RR024975NHLBI NIH HHS R01 HL090664NHLBI NIH HHS R21 HL106446NIAID NIH HHS R01 AI059108NIAID NIH HHS R01 AI070672NIAID NIH HHS U19 AI095227NIGMS NIH HHS GM015431NIGMS NIH HHS P01 GM015431NIGMS NIH HHS P50 GM015431
6 · The paper itself

Abstract

backgroundViral respiratory infection has long been known to influence the occurrence of asthma exacerbations. Over the last 20years much effort has been put into clarifying the role that viral respiratory infections play in the eventual development of asthma. SCOPE OF REVIEW: In this review we give a general background of the role of viruses in the processes of asthma exacerbation and asthma induction. We review recent additions to the literature in the last 3years with particular focus on clinical and epidemiologic investigations of influenza, rhinovirus, bocavirus, respiratory syncytial virus, and metapneumovirus. MAJOR

conclusionsThe development of asthma emerges from a complex interaction of genetic predisposition and environmental factors with viral infection likely playing a significant role in the effect of environment on asthma inception. This article is part of a Special Issue entitled: Biochemistry of Asthma. GENERAL SIGNIFICANCE: Further understanding of the role that viruses play in asthma exacerbation and inception will contribute to decreased asthma morbidity in the future. This article is part of a Special Issue entitled: Biochemistry of Asthma.

Indexed as

AsthmaHuman bocavirusHumansInfluenza, HumanParvoviridae InfectionsPicornaviridae InfectionsRespiratory Syncytial Virus InfectionsRhinovirusVirus Diseases

Identifiers

PMID21291960
PMCPMC3130828
OpenAlexW2008573343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.