ArticleJournal of neuroscience methods2011
Analyzing the dynamics of brain circuits with temperature: design and implementation of a miniature thermoelectric device.
Article in Journal of neuroscience methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Wireless, Adaptable and Fully Implantable Battery-powered Devices for Optical Stimulation of the Spinal Cord in Small Rodents.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Temperature robustness of the timing network within songbird premotor nucleus HVC.Journal of computational neuroscience · 2026Article
- Sapphire-Based Optrode for Low Noise Neural Recording and Optogenetic Manipulation.ACS chemical neuroscience · 2025Article
- Selective activation of mesoscale functional circuits via multichannel infrared stimulation of cortical columns in ultra-high-field 7T MRI.Cell reports methods · 2025Article
- Human TRPV1 is an efficient thermogenetic actuator for chronic neuromodulation.Cellular and molecular life sciences : CMLS · 2024Article
- Using temperature to analyze the neural basis of a time-based decision.Nature neuroscience · 2023Article
- Selective head cooling in the acute phase of concussive injury: a neuroimaging study.Frontiers in neurology · 2023Article
- Cytostatic hypothermia and its impact on glioblastoma and survival.Science advances · 2022Article
- Wireless implantable optical probe for continuous monitoring of oxygen saturation in flaps and organ grafts.Nature communications · 2022Article
- Brain temperature affects quantitative features of hippocampal sharp wave ripples.Journal of neurophysiology · 2022Article
- Review
- Wireless multilateral devices for optogenetic studies of individual and social behaviors.Nature neuroscience · 2021Article
- Cooling of Medial Septum Reveals Theta Phase Lag Coordination of Hippocampal Cell Assemblies.Neuron · 2020Article
- The promise and perils of causal circuit manipulations.Current opinion in neurobiology · 2018Review
- Paradoxical vocal changes in a trained singer by focally cooling the right superior temporal gyrus.Cortex; a journal devoted to the study of the nervous system and behavior · 2017Article
- Temperature Manipulation in Songbird Brain Implicates the Premotor Nucleus HVC in Birdsong Syntax.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017Article
- Article
- Conduction block of mammalian myelinated nerve by local cooling to 15-30°C after a brief heating.Journal of neurophysiology · 2016Article
- Modeling the Spatiotemporal Dynamics of Light and Heat Propagation for In Vivo Optogenetics.Cell reports · 2015Article
- Representation of interval timing by temporally scalable firing patterns in rat prefrontal cortex.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Traditional lesion or inactivation methods are useful for determining if a given brain area is involved in the generation of a behavior, but not for determining if circuit dynamics in that area control the timing of the behavior. In contrast, localized mild cooling or heating of a brain area alters the speed of neuronal and circuit dynamics and can reveal the role of that area in the control of timing. It has been shown that miniaturized solid-state heat pumps based on the Peltier effect can be useful for analyzing brain dynamics in small freely behaving animals (Long and Fee, 2008). Here we present a theoretical analysis of these devices and a procedure for optimizing their design. We describe the construction and implementation of one device for cooling surface brain areas, such as cortex, and another device for cooling deep brain regions. We also present measurements of the magnitude and localization of the brain temperature changes produced by these two devices.
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Registered trials
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