Evidence map›Paper›PMID 21290304›Full record

ReviewAdvances in experimental medicine and biology2011

C. elegans TRP channels.

Rui Xiao, X Z Shawn Xu

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Hierarchical behavior control by a single class of interneurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Shear stress sensing in C. elegans.Current biology : CB · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Diethylcarbamazine, TRP channels and CaScientific reports · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. TRP channels as potential targets for antischistosomals.International journal for parasitology. Drugs and drug resistance · 2018
    Review
  19. Article
  20. TRP channels in schistosomes.International journal for parasitology. Drugs and drug resistance · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rui XiaoDepartment of Molecular and Integrative Physiology, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA. rxiao@umich.edu
X Z Shawn Xu
University of Michigan–Ann Arbor · US

Funding

Mechanisms of Nicotine-Induced BehaviorsR01DA022316 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, SHAWN · 2007 to 2011
$1.5M
TRP Channel Function and RegulationR01GM078276 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, SHAWN · 2006 to 2010
$1.4M
NIDA NIH HHS R01 DA022316NIGMS NIH HHS R01 GM078276
6 · The paper itself

Abstract

Transient receptor potential (TRP) channels represent a superfamily of cation channels found in all eukaryotes. The C. elegans genome encodes seventeen TRP channels covering all of the seven TRP subfamilies. Genetic analyses in C. elegans have implicated TRP channels in a wide spectrum of behavioral and physiological processes, ranging from sensory transduction (e.g. chemosensation, touch sensation, proprioception and osmosensation) to fertilization, drug dependence, organelle biogenesis, apoptosis, gene expression, and neurotransmitter/hormone release. Many C. elegans TRP channels share similar activation and regulatory mechanisms with their vertebrate counterparts. Studies in C. elegans have also revealed some previously unrecognized functions and regulatory mechanisms of TRP channels. C. elegans represents an excellent genetic model organism for the study of function and regulation of TRP channels in vivo.

Indexed as

AnimalsCaenorhabditis elegansModels, GeneticTransient Receptor Potential ChannelsTransient Receptor Potential Channels

Identifiers

PMID21290304
PMCPMC3055911
OpenAlexW1549084543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.