ArticleMetallomics : integrated biometal science2011
Copper(II) enhances membrane-bound α-synuclein helix formation.
Article in Metallomics : integrated biometal science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 28 citations in OpenAlex.
- Article
- Discovery of structural and functional transition sites for membrane-penetrating activity of sheep myeloid antimicrobial peptide-18.Scientific reports · 2023Article
- Stability of HA2 Prefusion Structure and pH-Induced Conformational Changes in the HA2 Domain of H3N2 Hemagglutinin.Biochemistry · 2021Article
- Copper Dependent Modulation of α-Synuclein Phosphorylation in Differentiated SHSY5Y Neuroblastoma Cells.International journal of molecular sciences · 2021Article
- Navigating the dynamic landscape of alpha-synuclein morphology: a review of the physiologically relevant tetrameric conformation.Neural regeneration research · 2020Review
- Iron Redox Chemistry and Implications in the Parkinson's Disease Brain.Oxidative medicine and cellular longevity · 2019Review
- Coherent and Contradictory Facts, Feats and Fictions Associated with Metal Accumulation in Parkinson's Disease: Epicenter or Outcome, Yet a Demigod Question.Molecular neurobiology · 2017Review
- PhosphorylatedParkinson's disease · 2017Review
- Coordination of copper to the membrane-bound form of α-synuclein.Biochemistry · 2013Article
- Conversion of natively unstructured α-synuclein to its α-helical conformation significantly attenuates production of reactive oxygen species.Journal of inorganic biochemistry · 2013Article
- Alpha-synuclein functions in the nucleus to protect against hydroxyurea-induced replication stress in yeast.Human molecular genetics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Interactions of copper and membranes with α-synuclein have been implicated in pathogenic mechanisms of Parkinson's disease, yet work examining both concurrently is scarce. We have examined the effect of copper(ii) on protein/vesicle binding and found that both the copper(ii) affinity and α-helical content are enhanced for the membrane-bound protein.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.