Evidence map›Paper›PMID 21289649›Full record

ArticleNature structural & molecular biology2011

Measles virus fusion shifts into gear.

Erica Ollmann Saphire, Michael B A Oldstone

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature structural & molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Syncytia Formation in Oncolytic Virotherapy.Molecular therapy oncolytics · 2019
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Erica Ollmann SaphireDepartment of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, USA.
Michael B A Oldstone

Funding

PATHOGENESIS OF PERSISTENT VIRAL INFECTIONR01AI009484 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI OLDSTONE, MICHAEL B · 1985 to 2016
$7.2M
ARENAVIRUS RECEPTOR--STRUCTURE/FUNCTION STUDIESR01AI045927 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI OLDSTONE, MICHAEL B · 2000 to 2010
$3.6M
EBOLA VIRAL GLYCOPROTEINS: STRUCTURAL ANALYSISR01AI067927 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI SAPHIRE, ERICA OLLMANN · 2006 to 2013
$3.6M
Immunotherapeutics vs Ebola Sudan: Development, Structural & Functional AnalysisU01AI070530 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI SAPHIRE, ERICA OLLMANN · 2006 to 2010
$3.5M
Recombinant antigen diagnostics for filovirusesR44AI088843 · NIAID · ZALGEN LABS, LLC · PI BOISEN, MATTHEW L · 2014 to 2016
$3.0M
Analysis of immunotherapeutics to native Marburg virus epitopesR01AI089498 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI SAPHIRE, ERICA OLLMANN · 2010 to 2014
$2.9M
STRUCTURE DRIVEN ANALYSIS OF EBOLA VIRUS RECEPTOR BINDING SITER01AI081982 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI SAPHIRE, ERICA OLLMANN · 2010 to 2014
$2.8M
In Vivo Analysis of T lymphocytes in the Persistently Infected CNSR01AI070967 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI OLDSTONE, MICHAEL B · 2007 to 2011
$2.3M
Immunotherapeutics against Marburg: Development, structural & functional anaylsisU01AI082156 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI SAPHIRE, ERICA OLLMANN · 2009 to 2010
$1.3M
Recombinant antigen diagnostics for filovirusesR43AI088843 · NIAID · CORGENIX MEDICAL CORPORATION · PI LOPEZ, LUIS R. · 2010 to 2011
$590k
PATHOGENESIS OF PERSISTENT VIRAL INFECTIONR37AI009484 · NIAID · SCRIPPS RESEARCH INSTITUTE · PI OLDSTONE, MICHAEL B · 1988 to 1997
–
NIAID NIH HHS AI009484NIAID NIH HHS AI045927NIAID NIH HHS AI067927NIAID NIH HHS AI070530NIAID NIH HHS AI070967NIAID NIH HHS AI081982NIAID NIH HHS AI082156NIAID NIH HHS AI088843NIAID NIH HHS AI089498NIAID NIH HHS R01 AI067927NIAID NIH HHS R01 AI081982NIAID NIH HHS R01 AI089498NIAID NIH HHS R44 AI088843NIAID NIH HHS U01 AI070530NIAID NIH HHS U01 AI082156PHS HHS HSSN27220090049C
6 · The paper itself

Abstract

In this issue, two papers present contrasting models for the machinations of the measles virus attachment protein. Here we discuss how these reports illuminate possible intersubunit motions made by the protein as it drives the fusion of viral and cellular membranes during infection and further our understanding of this global scourge.

Indexed as

Virus InternalizationAnimalsAntigens, CDHemagglutinins, ViralHumansMeaslesMeasles virusProtein BindingProtein ConformationReceptors, Cell SurfaceSignaling Lymphocytic Activation Molecule Family Member 1Virus AttachmentAntigens, CDHemagglutinins, ViralReceptors, Cell SurfaceSignaling Lymphocytic Activation Molecule Family Member 1

Identifiers

PMID21289649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.