Evidence map›Paper›PMID 21289533›Full record

ReviewPediatric research2011

Sensory processing in autism: a review of neurophysiologic findings.

Elysa J Marco, Leighton B N Hinkley, Susanna S Hill, Srikantan S Nagarajan

2 registry-linked trialsAbstract readReview
In one paragraph

Review in Pediatric research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 506 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
506citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05752994 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effect of Multisensory Environment Room on Behavior in Children With Autism Spectrum Disorder

TypeinterventionalSponsorMahidol UniversityRan2023 to 2024Enrolled30ConditionsAutism Spectrum Disorder, AutismArmsTraining in the multisensory room environment, Home program
NCT07743177 active not recruitingnot on this mapstarted 2026, after this paper: background citation

Auditory Brainstem Evoked Potentials in Autism Spectrum Disorder: A Window on Neural Maturation and Sex Differences

TypeobservationalSponsorIRCCS National Neurological Institute "C. Mondino" FoundationRan2026 to 2028Enrolled200ConditionsAutism Spectrum Disorder
3 · Its place in the literature

Who cites it

506 citing papers in PubMed, 14 syntheses or guidelines pooled it.

  1. Auditory Sensitivity in Autism: A Systematic Review of Mismatch Negativity and Mismatch Field Responses.Autism research : official journal of the International Society for Autism Research · 2026
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  9. First Impressions Towards Autistic People: A Systematic Review and Meta-Analysis.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
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  13. Sensory processing and eating behaviours in autism: A systematic review.European eating disorders review : the journal of the Eating Disorders Association · 2022
    Pooled it
  14. Auditory processing in rodent models of autism: a systematic review.Journal of neurodevelopmental disorders · 2022
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446 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elysa J MarcoDepartment of Neurology, University of California, San Francisco, California 94143, USA. marcoe@neuropeds.ucsf.edu
Leighton B N Hinkley
Susanna S Hill
Srikantan S Nagarajan

Funding

Cortical spatiotemporal plasticity in humansR01DC004855 · NIDCD · UNIVERSITY OF UTAH · PI NAGARAJAN, SRIKANTAN S. · 2002 to 2011
$2.9M
Magnetic Source Imaging and Sensory Behavioral Characterization in AutismK23MH083890 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MARCO, ELYSA JILL · 2008 to 2011
$695k
NIDCD NIH HHS R01 DC004855NIMH NIH HHS K23 MH083890
6 · The paper itself

Abstract

Atypical sensory-based behaviors are a ubiquitous feature of autism spectrum disorders (ASDs). In this article, we review the neural underpinnings of sensory processing in autism by reviewing the literature on neurophysiological responses to auditory, tactile, and visual stimuli in autistic individuals. We review studies of unimodal sensory processing and multisensory integration that use a variety of neuroimaging techniques, including electroencephalography (EEG), magnetoencephalography (MEG), and functional MRI. We then explore the impact of covert and overt attention on sensory processing. With additional characterization, neurophysiologic profiles of sensory processing in ASD may serve as valuable biomarkers for diagnosis and monitoring of therapeutic interventions for autism and reveal potential strategies and target brain regions for therapeutic interventions.

Indexed as

AttentionAuditory Perceptual DisordersAutistic DisorderHumansTouch PerceptionVisual Perception

Identifiers

PMID21289533
PMCPMC3086654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.