ArticleSchizophrenia research2011
Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS).
Article in Schizophrenia research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Verbal learning and hippocampal dysfunction in schizophrenia: A meta-analysis.Neuroscience and biobehavioral reviews · 2018Pooled it
- The progression of disorder-specific brain pattern expression in schizophrenia over 9 years.NPJ schizophrenia · 2021Article
- Where have I heard that before? A validity study of source memory indices from the California Verbal Learning Test - Second edition.The Clinical neuropsychologist · 2020Article
- Associations between psychosis endophenotypes across brain functional, structural, and cognitive domains.Psychological medicine · 2018Article
- Recent Advances in the Genetics of Schizophrenia.Molecular neuropsychiatry · 2018Review
- Prioritizing schizophrenia endophenotypes for future genetic studies: An example using data from the COGS-1 family study.Schizophrenia research · 2016Article
- Interaction between COMT rs5993883 and second generation antipsychotics is linked to decreases in verbal cognition and cognitive control in bipolar disorder.BMC psychology · 2016Article
- Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study.Schizophrenia research · 2016Review
- Cognitive endophenotypes inform genome-wide expression profiling in schizophrenia.Neuropsychology · 2016Article
- California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS).Schizophrenia research · 2015Article
- Consortium on the Genetics of Schizophrenia (COGS) assessment of endophenotypes for schizophrenia: an introduction to this Special Issue of Schizophrenia Research.Schizophrenia research · 2015Review
- Factor structure and heritability of endophenotypes in schizophrenia: findings from the Consortium on the Genetics of Schizophrenia (COGS-1).Schizophrenia research · 2015Article
- Paternal age of schizophrenia probands and endophenotypic differences from unaffected siblings.Psychiatry research · 2014Article
- Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia?PloS one · 2014Article
- Clinical phenotypes of psychosis in the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP).The American journal of psychiatry · 2013Article
- Sex differences in familiality effects on neurocognitive performance in schizophrenia.Biological psychiatry · 2013Article
- On the simple and the complex in psychiatry, with reference to DSM 5 and research domain criteria.Journal of psychiatry & neuroscience : JPN · 2013Article
- Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia.The American journal of psychiatry · 2013Article
- Article
Corrections and comments
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Authors and funding
27 authors at 10 institutions in 1 country.
Funding
Abstract
Genetic studies of schizophrenia focus increasingly on putative endophenotypes because their genetic etiology may be simpler than clinical diagnosis. The Consortium on the Genetics of Schizophrenia (COGS), a multisite family study, aims to identify the genetic basis of several endophenotypes including verbal declarative memory (VDM), a neurocognitive function that shows robust impairment in schizophrenia. We present data on one type of measure of VDM, the California Verbal Learning Test, Second Edition (CVLT-II), in schizophrenia probands (n=305), their full biological siblings (n=449) and parents (n=232), and in community comparison subjects (CCS; n=509) across seven sites. Probands performed more poorly on each of five CVLT-II measures compared to related sibling and parent groups and CCS. Siblings and parents performed significantly worse than CCS on one measure (Discriminability), but with smaller effect sizes and less impairment than observed previously. The results raise questions about the homogeneity of VDM as an endophenotype, about methodological issues related to sampling, and about psychometric issues that impact the utility of the CVLT for detecting VDM deficits in nonpsychotic relatives of persons with schizophrenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.