ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2011
Clinico-radiological outcomes following gamma knife radiosurgery for pediatric arteriovenous malformations.
Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Stereotactic radiosurgery treatment of pediatric arteriovenous malformations: a PRISMA systematic review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Pooled it
- Pediatric cranial stereotactic radiosurgery: Meta-analysis and international stereotactic radiosurgery society practice guidelines.Neuro-oncology · 2025Guideline
- Trapped temporal horn: From theory to practice, a systematic review of current understanding and future perspectives.World neurosurgery: X · 2024Review
- Entrapment of the temporal horn secondary to postoperative gamma-knife radiosurgery in intraventricular meningioma: A case report.World journal of clinical cases · 2019Article
- Radiosurgical treatment of arteriovenous malformations in a retrospective study group of 33 children: the importance of radiobiological scores.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Clinical outcomes and radiosurgical considerations for pediatric arteriovenous malformation: influence of clinical features on obliteration rate.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2017Article
- Angiographic features help predict outcome after stereotactic radiosurgery for the treatment of pediatric arteriovenous malformations.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Stereotactic linac radiosurgery and hypofractionated stereotactic radiotherapy for pediatric arteriovenous malformations of the brain: experiences of a single institution.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2013Article
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5 authors at 2 institutions in 1 country.
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Abstract
purposeThe aim of this study was to evaluate clinico-radiological outcomes following gamma knife radiosurgery (GKS) for pediatric arteriovenous malformations (AVMs).
methodsThe present series included 39 children (3-17 years of age) who underwent GKS for cerebral AVMs between January 2002 and February 2008. Twenty-five patients presented with hemorrhages. The median AVM volume was 1.5 cm³, and the median marginal dose was 20 Gy. All patients continued to have follow-up for more than 24 months with serial magnetic resonance images (MRIs)/angiograms. Current school performance has been evaluated using a telephone survey answered by the patients' parents.
resultsFollow-up angiograms, available in 34 patients, confirmed complete obliteration in 16 patients. Serial MRIs indicated obliteration of the nidus in one of five patients without angiography. The diffuse nidus structure and low marginal dose were significantly associated with incomplete obliteration. Twelve patients underwent a second GKS, and subsequent angiographies, available in six patients, demonstrated complete obliteration in two of them. Complications included new-onset seizures (n = 1), apraxia (n = 1), and temporal horn entrapment requiring a shunt operation (n = 1). School performance declined in 14 out of 32 patients. Both the AVM volume and modified AVM score were found to be reliable predictors of school performance.
conclusionsThe results of the present study substantiate the diffuse and other atypical features of pediatric AVMs as major determinants of treatment failure following GKS. Considering the apparent declination of school performance, future prospective studies would be required to investigate the possible late-effects of GKS on neuropsychological function.
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