ArticleJournal of comparative physiology. B, Biochemical, systemic, and environmental physiology2011
Growing old with the immune system: a study of immunosenescence in the zebra finch (Taeniopygia guttata).
Article in Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 32 citations in OpenAlex.
- Immune gene expression dynamics across the lifespan of Tibetan macaques (Current zoology · 2026Article
- Nonspecific constitutive immunity is negatively associated with basal metabolic rate at early phase of territorial competition in males of great tit.Current zoology · 2026Article
- Wild Florida mottled ducks demonstrate strong heterogeneity in their humoral innate immune response.PloS one · 2025Article
- Snap-freezing in the Field: Effect of Sample Holding Time on Performance of Bactericidal Assays.Integrative and comparative biology · 2022Article
- Using Blood Transcriptome Analysis to Determine the Changes in Immunity and Metabolism of Giant Pandas with Age.Veterinary sciences · 2022Article
- Variations in immune parameters with age in a wild rodent population and links with survival.Ecology and evolution · 2022Article
- New Perspectives on Avian Models for Studies of Basic Aging Processes.Biomedicines · 2021Review
- Comparative Analysis of the Gut Microbial Communities of the Eurasian Kestrel (Frontiers in microbiology · 2020Article
- Transcriptome analysis reveals immune-related gene expression changes with age in giant panda (Aging · 2019Article
- Antibody responses to avian influenza viruses in wild birds broaden with age.Proceedings. Biological sciences · 2016Article
- Host sex and age influence endoparasite burdens in the gray mouse lemur.Frontiers in zoology · 2015Article
- Extrinsic- and intrinsic-dependent variation in component communities and patterns of aggregations in helminth parasites of great cormorant (Phalacrocorax carbo) from N.E. Poland.Parasitology research · 2014Article
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3 authors at 2 institutions in 1 country.
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Abstract
Immunosenescence has not received much attention in birds and the few existing studies indicate that the occurrence of immunosenescence and/or its extent may differ between species. In addition, not much information is available on the immunosenescence patterns of different immune parameters assessed simultaneously in both sexes within a single species. The present study reports the results on immunosenescence in innate immunity and both cellular and humoral acquired immunity of both sexes in a captive population of zebra finch (Taeniopygia guttata) using three age groups (approximately 0.2, 2.5 and 5.1 years). Both male and female finches showed an inverse U-shaped pattern in cellular immune function with age, quantified by a PHA response. Males showed stronger responses than females at all ages. In contrast, an increase with age in humoral immunity, quantified through total plasma immunoglobulin Y levels, was found in both sexes. However, our measurements of innate immunity measured through the bacteria-killing ability against Escherichia coli gave inconclusive results. Still, we conclude that both cellular and humoral acquired immunity are susceptible to immunosenescence, and that the sexes differ in cellular immunity.
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