ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2011
Local interneuron diversity in the primary olfactory center of the moth Manduca sexta.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 49 citations in OpenAlex.
- Connectivity of serotonin neurons reveals a constrained inhibitory subnetwork within the olfactory system.Journal of neurophysiology · 2026Article
- Emerging tools to advance neuroethology in butterflies and moths.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Multi-unit recordings in the stick insectFrontiers in physiology · 2026Article
- Differential modulation of feedforward inhibition reflects topographic organization in the olfactory system.Nature communications · 2025Article
- Neuron synchronization analyzed through spatial-temporal attention.Frontiers in computational neuroscience · 2025Article
- Article
- Antennal-lobe neurons in the moth Helicoverpa armigera: Morphological features of projection neurons, local interneurons, and centrifugal neurons.The Journal of comparative neurology · 2021Article
- Short term depression, presynaptic inhibition and local neuron diversity play key functional roles in the insect antennal lobe.Journal of computational neuroscience · 2020Article
- Glomerular Organization in the Antennal Lobe of the Oriental Fruit FlyFrontiers in neuroanatomy · 2018Article
- Intrinsic and Extrinsic Neuromodulation of Olfactory Processing.Frontiers in cellular neuroscience · 2017Review
- Coincidence of pheromone and plant odor leads to sensory plasticity in the heliothine olfactory system.PloS one · 2017Article
- Serotonergic Modulation Differentially Targets Distinct Network Elements within the Antennal Lobe of Drosophila melanogaster.Scientific reports · 2016Article
- The anatomical basis for modulatory convergence in the antennal lobe of Manduca sexta.The Journal of comparative neurology · 2016Article
- A Flight Sensory-Motor to Olfactory Processing Circuit in the Moth Manduca sexta.Frontiers in neural circuits · 2016Article
- Neuroethology of Olfactory-Guided Behavior and Its Potential Application in the Control of Harmful Insects.Frontiers in physiology · 2016Review
- Two types of local interneurons are distinguished by morphology, intrinsic membrane properties, and functional connectivity in the moth antennal lobe.Journal of neurophysiology · 2015Article
- Trade-off between information format and capacity in the olfactory system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- The neural bases of host plant selection in a Neuroecology framework.Frontiers in physiology · 2015Review
- Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Local interneurons (LNs) play important roles in shaping and modulating the activity of output neurons in primary olfactory centers. Here, we studied the morphological characteristics, odor responses, and neurotransmitter content of LNs in the antennal lobe (AL, the insect primary olfactory center) of the moth Manduca sexta. We found that most LNs are broadly tuned, with all LNs responding to at least one odorant. 70% of the odorants evoked a response, and 22% of the neurons responded to all the odorants tested. Some LNs showed excitatory (35%) or inhibitory (33%) responses only, while 33% of the neurons showed both excitatory and inhibitory responses, depending on the odorant. LNs that only showed inhibitory responses were the most responsive, with 78% of the odorants evoking a response. Neurons were morphologically diverse, with most LNs innervating almost all glomeruli and others innervating restricted portions of the AL. 61 and 39% of LNs were identified as GABA-immunoreactive (GABA-ir) and non-GABA-ir, respectively. We found no correlations between odor responses and GABA-ir, neither between morphology and GABA-ir. These results show that, as observed in other insects, LNs are diverse, which likely determines the complexity of the inhibitory network that regulates AL output.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.