ArticleSleep2011
Daytime sleepiness and REM sleep characteristics in myotonic dystrophy: a case-control study.
Article in Sleep, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- A systematic review of the frequency of sleep evaluations, sleep disorders, and treatments among individuals with muscular dystrophy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Pooled it
- Psychostimulants for hypersomnia (excessive daytime sleepiness) in myotonic dystrophy.The Cochrane database of systematic reviews · 2024Pooled it
- Diagnosing sleep disordered breathing in patients with chronic pulmonary disease: which test for which patient?Breathe (Sheffield, England) · 2023Article
- Myotonic dystrophy type 1 presenting with dyspnea: A case report.World journal of clinical cases · 2022Article
- Assessment of self-reported and objective daytime sleepiness in adult-onset myotonic dystrophy type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Subjective-objective sleepiness discrepancy in adult-onset myotonic dystrophy type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Excessive daytime sleepiness and fatigue in neurological disorders.Sleep & breathing = Schlaf & Atmung · 2020Review
- Predicting daytime sleepiness and fatigue: a 9-year prospective study in myotonic dystrophy type 1.Journal of neurology · 2020Article
- Sleep Disorders in Four Patients With Myotonic Dystrophy Type 1.Frontiers in neurology · 2020Article
- Perceived fatigue in myotonic dystrophy type 1: a case-control study.BMC neurology · 2019Article
- Sleep Complaints, Sleep and Breathing Disorders in Myotonic Dystrophy Type 2.Current neurology and neuroscience reports · 2019Review
- Comparative Sleep Disturbances in Myotonic Dystrophy Types 1 and 2.Current neurology and neuroscience reports · 2018Review
- Increased EEG Theta Spectral Power in Sleep in Myotonic Dystrophy Type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018Article
- Orexin/hypocretin levels in the cerebrospinal fluid and characteristics of patients with myotonic dystrophy type 1 with excessive daytime sleepiness.Neuropsychiatric disease and treatment · 2018Article
- [Sleep and neurological diseases].Der Nervenarzt · 2016Review
- Congenital and childhood myotonic dystrophy: Current aspects of disease and future directions.World journal of clinical pediatrics · 2015Review
- Neuromuscular disorders and sleep in critically ill patients.Critical care clinics · 2015Review
- Central Disorders of Hypersomnolence: Focus on the Narcolepsies and Idiopathic Hypersomnia.Chest · 2015Review
- Diagnosis of muscle diseases presenting with early respiratory failure.Journal of neurology · 2015Review
- Evaluation of CNS involvement in myotonic dystrophy type 1 and type 2 by transcranial sonography.Journal of neurology · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesExcessive daytime sleepiness (EDS) and high daytime REM sleep pressure are important sleep features of myotonic dystrophy (DM1). Small and uncontrolled studies have focused on EDS phenotype; none have focused on nocturnal REM sleep characteristics in DM1. Our objectives were to compare polysomnographic and multiple sleep latency test (MSLT) parameters, and both tonic and phasic components of REM sleep between DM1 and controls. DESIGN AND PATIENTS: Forty consecutive DM1 patients and 40 sex- and age-matched controls were included. All subjects underwent overnight polysomnography followed by a MSLT.
resultsAbout 80% of DM1 patients complained of EDS through clinical interview: 31.4% had Epworth scores > 10, and 12.5% had objective sleepiness (latency < 8 min). Higher apnea and central apnea indexes, and a greater proportion of subjects with severe apnea/hypopnea syndrome were found in DM1. The number of SOREMP differed between DM1 and controls, one and two SOREMPs being present in 47.5% and 32.5%, and one control had one SOREMP. Higher percentages of slow wave sleep and REM sleep were found in DM1. DM1 patients had significantly more PLMW, PLMS in both NREM and REM sleep, and PLMS-associated microarousals. Higher REM density was found in DM1 with similar tendencies for either REM sleep without atonia or phasic EMG activity.
conclusionsThis is the first case-control sleep study in DM1 to demonstrate higher frequency of daytime sleepiness and abnormalities in REM sleep regulation, with an increased daytime and nighttime REM sleep propensity, REM density, and PLMS. These data suggest a primary central sleep regulation dysfunction in DM1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.