ArticlePLoS genetics2011
Segregating variation in the polycomb group gene cramped alters the effect of temperature on multiple traits.
Article in PLoS genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.Evolution; international journal of organic evolution · 2026Article
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.bioRxiv : the preprint server for biology · 2025Article
- Molecular mechanisms underlying the evolution of a color polyphenism by genetic accommodation in the tobacco hornworm,Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Polycomb group proteins confer robustness to aposematic coloration in the milkweed bug,Proceedings. Biological sciences · 2024Article
- Transcriptional regulation underlying the temperature response of embryonic development rate in the winter moth.Molecular ecology · 2022Article
- Assessing the toxic effects of bisphenol A in consumed crayfish Astacus leptodactylus using multi biochemical markers.Environmental science and pollution research international · 2022Article
- The Paramount Role ofInsects · 2021Review
- Differences in temperature-sensitive expression of PcG-regulated genes among natural populations of Drosophila melanogaster.G3 (Bethesda, Md.) · 2021Article
- Decreased Temperature Sensitivity ofGenes · 2019Article
- Genetics of adaptation in modern chicken.PLoS genetics · 2019Article
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- Pigmentation in Drosophila melanogaster reaches its maximum in Ethiopia and correlates most strongly with ultra-violet radiation in sub-Saharan Africa.BMC evolutionary biology · 2014Article
- A perspective on micro-evo-devo: progress and potential.Genetics · 2013Review
- The microRNA miR-8 is a positive regulator of pigmentation and eclosion in Drosophila.Developmental dynamics : an official publication of the American Association of Anatomists · 2012Article
- Genetic basis for developmental homeostasis of germline stem cell niche number: a network of Tramtrack-Group nuclear BTB factors.PloS one · 2012Article
- Distinct functional constraints partition sequence conservation in a cis-regulatory element.PLoS genetics · 2011Article
- The Polycomb group protein CRAMPED is involved with TRF2 in the activation of the histone H1 gene.Chromosoma · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The phenotype produced by a given genotype can be strongly modulated by environmental conditions. Therefore, natural populations continuously adapt to environment heterogeneity to maintain optimal phenotypes. It generates a high genetic variation in environment-sensitive gene networks, which is thought to facilitate evolution. Here we analyze the chromatin regulator crm, identified as a candidate for adaptation of Drosophila melanogaster to northern latitudes. We show that crm contributes to environmental canalization. In particular, crm modulates the effect of temperature on a genomic region encoding Hedgehog and Wingless signaling effectors. crm affects this region through both constitutive heterochromatin and Polycomb silencing. Furthermore, we show that crm European and African natural variants shift the reaction norms of plastic traits. Interestingly, traits modulated by crm natural variants can differ markedly between Drosophila species, suggesting that temperature adaptation facilitates their evolution.
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