ArticlePloS one2011
Unveiling the role of Dps in the organization of mycobacterial nucleoid.
Article in PloS one, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Molecular Kaleidoscope of Nucleoid-Associated Proteins Regulatory Network and Chromosome Architecture in Mycobacterium Tuberculosis.Current microbiology · 2026Review
- Decoding the role of DNA sequence on protein-DNA co-condensation.PLoS computational biology · 2025Article
- Dps Functions as a Key Player in Bacterial Iron Homeostasis.ACS omega · 2023Review
- Mycobacterial IHF is a highly dynamic nucleoid-associated protein that assists HupB in organizing chromatin.Frontiers in microbiology · 2023Article
- Ferritin: A Promising Nanoreactor and Nanocarrier for Bionanotechnology.ACS bio & med chem Au · 2022Review
- Dps Is a Universally Conserved Dual-Action DNA-Binding and Ferritin Protein.Journal of bacteriology · 2022Review
- Small Prokaryotic DNA-Binding Proteins Protect Genome Integrity throughout the Life Cycle.International journal of molecular sciences · 2022Review
- Mycobacterial STAND adenylyl cyclases: The HTH domain binds DNA to form biocrystallized nucleoids.Biophysical journal · 2021Article
- An Overview of Dps: Dual Acting Nanovehicles in Prokaryotes with DNA Binding and Ferroxidation Properties.Sub-cellular biochemistry · 2021Review
- Transcription of Bacterial Chromatin.Journal of molecular biology · 2019Review
- Article
- The Oligomeric Form of the Escherichia coli Dps Protein Depends on the Availability of Iron Ions.Molecules (Basel, Switzerland) · 2017Article
- Global RNA association with the transcriptionally active chromosome of chloroplasts.Plant molecular biology · 2017Article
- The nucleoid protein Dps binds genomic DNA of Escherichia coli in a non-random manner.PloS one · 2017Article
- Modes of Escherichia coli Dps Interaction with DNA as Revealed by Atomic Force Microscopy.PloS one · 2015Article
- A histidine aspartate ionic lock gates the iron passage in miniferritins from Mycobacterium smegmatis.The Journal of biological chemistry · 2014Article
- Mechanism of DNA organization by Mycobacterium tuberculosis protein Lsr2.Nucleic acids research · 2013Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to preserve genetic information in stress conditions, bacterial DNA is organized into higher order nucleoid structure. In this paper, with the help of Atomic Force Microscopy, we show the different structural changes in mycobacterial nucleoid at different points of growth in the presence of different concentrations of glucose in the medium. We also observe that in Mycobacterium smegmatis, two different Dps proteins (Dps1 and Dps2) promote two types of nucleoid organizations. At the late stationary phase, under low glucose availability, Dps1 binds to DNA to form a very stable toroid structure. On the other hand, under the same condition, Dps2-DNA complex forms an incompletely condensed toroid and finally forms a further stable coral reef structure in the presence of RNA. This coral reef structure is stable in high concentration of bivalent ion like Mg(2+).
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