Evidence map›Paper›PMID 21282552›Full record

ReviewHypertension (Dallas, Tex. : 1979)2011

Intratubular renin-angiotensin system in hypertension.

L Gabriel Navar, Hiroyuki Kobori, Minolfa C Prieto, Romer A Gonzalez-Villalobos

Abstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 151 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
151citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

151 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. The relationship between estrogen and renin angiotensin system components in the context of hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Review
  6. Intercalated Cell ClC-K2 Channel Contributes to Systemic ClFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Kidney Renin-Angiotensin System: Lost in a RAS Cascade.Hypertension (Dallas, Tex. : 1979) · 2024
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Flexible and multifaceted: the plasticity of renin-expressing cells.Pflugers Archiv : European journal of physiology · 2022
    Review

91 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

L Gabriel NavarDepartment of Physiology, SL39, Tulane University Health Science Center, 1430 Tulane Ave, New Orleans, LA 70112, USA. navar@tulane.edu
Hiroyuki Kobori
Minolfa C Prieto
Romer A Gonzalez-Villalobos

Funding

TULANE COBRE: TRANSGENIC &GENE-TARGETED ANIMAL COREP20RR017659 · NCRR · TULANE UNIVERSITY OF LOUISIANA · PI NAVAR, LUIS GABRIEL · 2002 to 2011
$22.1M
Tulane Building Interdisciplinary Research Careers in Women's Health (BIRCWH)K12HD043451 · NICHD · TULANE UNIVERSITY OF LOUISIANA · PI KROUSEL-WOOD, MARIE · 2002 to 2023
$9.9M
Translational Research in Hypertension and Renal BiologyP30GM103337 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI NAVAR, LUIS GABRIEL · 2012 to 2016
$5.8M
Renal Function Derangements in HypertensionR01HL026371 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI NAVAR, LUIS GABRIEL · 1985 to 2010
$3.4M
Intrarenal Augmentation of Angiotensinogen by Ang IIR01DK072408 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI NAVAR, LUIS GABRIEL · 2006 to 2010
$1.2M
Intrarenal Angiotensin II generation during Angiotensin II-induced hypertensionK99DK083455 · NIDDK · TULANE UNIVERSITY OF LOUISIANA · PI GONZALEZ-VILLALOBOS, ROMER ANDRES · 2009 to 2010
$190k
NCRR NIH HHS P20 RR017659NCRR NIH HHS P20RR-017659NHLBI NIH HHS R01 HL026371NHLBI NIH HHS R01HL-26371NICHD NIH HHS K12 HD043451NIDDK NIH HHS 2K99DK-083455NIDDK NIH HHS K99 DK083455NIDDK NIH HHS R01 DK072408NIDDK NIH HHS R01DK-072408NIGMS NIH HHS P30 GM103337
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HumansHypertensionKidney TubulesReceptors, AngiotensinRenin-Angiotensin SystemReceptors, Angiotensin

Identifiers

PMID21282552
PMCPMC3073668

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.