Evidence map›Paper›PMID 21282449›Full record

ArticleAntimicrobial agents and chemotherapy2011

Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria.

Le Thi Minh Vien, Manal Abuoun, Victoria Morrison, Nicholas Thomson, James I Campbell, Martin J Woodward, Nguyen Van Vinh Chau, Jeremy Farrar, Constance Schultsz, Stephen Baker

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Case Report: Multidrug ResistantFrontiers in veterinary science · 2021
    Article
  3. Review
  4. Article
  5. Plasmid-mediated quinolone resistance.Microbiology spectrum · 2014
    Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Le Thi Minh VienThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Manal Abuoun
Victoria Morrison
Nicholas Thomson
James I Campbell
Martin J Woodward
Nguyen Van Vinh Chau
Jeremy Farrar
Constance Schultsz
Stephen Baker
Hospital for Tropical Diseases · VNUniversity of Oxford · GBWellcome Sanger Institute · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

The qnrS1 gene induces reduced susceptibility to fluoroquinolones in enterobacteria. We investigated the structure, antimicrobial susceptibility phenotype, and antimicrobial resistance gene characteristics of qnrS1 plasmids from hospitalized patients and community controls in southern Vietnam. We found that the antimicrobial susceptibilities, resistance gene characteristics, and plasmid structures of qnrS1 plasmids from the hospital differed from those from the community. Our data imply that the characteristics of the two plasmid groups are indicative of distinct selective pressures in the differing environments.

Indexed as

Anti-Bacterial AgentsBacterial ProteinsDrug Resistance, Multiple, BacterialEnterobacteriaceaeFluoroquinolonesGenotypeMicrobial Sensitivity TestsPlasmidsAnti-Bacterial AgentsBacterial ProteinsFluoroquinolones

Identifiers

PMID21282449
PMCPMC3067134
OpenAlexW2120124214

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.