ArticlePain2011
Increased wind-up to heat pain in women with a childhood history of functional abdominal pain.
Article in Pain, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
27 citing papers in PubMed, 39 citations in OpenAlex.
- Does Quantitative Sensory Testing Improve Prediction of Chronic Pain Trajectories? A Longitudinal Study of Youth With Functional Abdominal Pain Participating in a Randomized Controlled Trial of Cognitive Behavioral Treatment.The Clinical journal of pain · 2021Trial
- Biobehavioral Predictors of Pain Intensity, Pain Interference, and Chronic Pain Episodes: A Prospective Cohort Study of African-American Adults.The journal of pain · 2024Article
- Adversity type and timing predict temporal summation of pain in African-American adults.Journal of behavioral medicine · 2023Article
- Place and Pain: Association Between Neighborhood SES and Quantitative Sensory Testing Responses in Youth With Functional Abdominal Pain.Journal of pediatric psychology · 2022Article
- Self-reported specific learning disorders and risk factors among Hungarian adolescents with functional abdominal pain disorders: a cross sectional study.BMC pediatrics · 2020Article
- Women Undergoing Third Line Overactive Bladder Treatment Demonstrate Elevated Thermal Temporal Summation.The Journal of urology · 2018Article
- Is Resolution of Chronic Pain Associated With Changes in Blood Pressure-related Hypoalgesia?Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018Article
- Article
- Temporal summation to thermal stimuli is elevated in women with overactive bladder syndrome.Neurourology and urodynamics · 2017Article
- Chronic Pain in Children and Adolescents: Diagnosis and Treatment of Primary Pain Disorders in Head, Abdomen, Muscles and Joints.Children (Basel, Switzerland) · 2016Review
- Article
- Does central sensitization help explain idiopathic overactive bladder?Nature reviews. Urology · 2016Review
- State of the art in biobehavioral approaches to the management of chronic pain in childhood.Pain management · 2016Review
- Heightened Temporal Summation of Pain in Patients with Functional Gastrointestinal Disorders and History of Trauma.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2015Article
- Article
- Aberrant synaptic integration in adult lamina I projection neurons following neonatal tissue damage.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Attachment and adjustment in adolescents and young adults with a history of pediatric functional abdominal pain.The Clinical journal of pain · 2015Article
- Predicting persistence of functional abdominal pain from childhood into young adulthood.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2014Article
- Can agonistic striving lead to unexplained illness? Implicit goals, pain tolerance, and somatic symptoms in adolescents and adults.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2014Article
- Functional abdominal pain in childhood and long-term vulnerability to anxiety disorders.Pediatrics · 2013Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Idiopathic or functional abdominal pain (FAP) is common in school-age children and typically reflects a functional gastrointestinal disorder (FGID). FGIDs in adults have been distinguished by enhanced responses of the central nervous system to pain stimuli, known as central sensitization. This study investigated whether adolescents and young adults with a history of pediatric FAP (n=144), compared with well control subjects (n=78), showed enhanced central sensitization demonstrated by greater temporal summation (wind-up) to brief, repetitive heat pulses. We also assessed the role of gender and trait anxiety in wind-up to heat pain. Women with a history of FAP showed greater wind-up to heat pain than men with a history of FAP (P<.05) and well control subjects of both genders (P<.05). Results were similar for FAP participants whose abdominal pain was ongoing at follow-up and those whose pain had resolved. Although anxiety was significantly higher in the FAP group compared with control subjects (P<.01) and in women compared with men (P<.05), anxiety did not explain the increased wind-up observed in women with a childhood history of FAP. Results suggest that women with a pediatric history of FAP may have a long-term vulnerability to pain associated with enhanced central nervous system responses to pain stimuli. Young women with a childhood history of functional abdominal pain may have a long-term vulnerability to pain that is associated with enhanced responses of the central nervous system to pain stimuli.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.