Evidence map›Paper›PMID 21280900›Full record

ArticleJournal of biomedical optics

Light scattering of human red blood cells during metabolic remodeling of the membrane.

YongKeun Park, Catherine A Best-Popescu, Ramachandra R Dasari, Gabriel Popescu

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical optics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  3. Biomedical optics express · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

YongKeun ParkMassachusetts Institute of Technology, G. R. Harrison Spectroscopy Laboratory, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA. yk.park@kaist.ac.kr
Catherine A Best-Popescu
Ramachandra R Dasari
Gabriel Popescu
Massachusetts Institute of Technology · USUniversity of Illinois Urbana-Champaign · US

Funding

WIDE-FIELD REFLECTION PHASE MICROSCOPYP41RR002594 · NCRR · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI PARK, YOUNGKYU · 1985 to 2011
$12.3M
NCI NIH HHS R21: CA154813NCRR NIH HHS P41 RR002594NCRR NIH HHS P41-RR02594-18-24
6 · The paper itself

Abstract

We present the light scattering properties of individual human red blood cells (RBCs). We show that both the RBC static and dynamic scattering signals are altered by adenosine 5'-triphosphate (ATP)-driven membrane metabolic remodeling. To measure the light scattering signal from individual RBCs, we use diffraction phase microscopy together with a Fourier transform light scattering technique. RBC cytosolic ATPs are both chemically and metabolically depleted, and the corresponding scattering signals are compared with the light scattering signal of normal RBCs having physiologic levels of ATP.

Indexed as

Adenosine TriphosphateCells, CulturedErythrocyte MembraneHumansLightNephelometry and TurbidimetryScattering, RadiationAdenosine Triphosphate

Identifiers

PMID21280900
PMCPMC3041812
OpenAlexW2146519452

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.