Evidence map›Paper›PMID 21280838›Full record

ArticleThe Review of scientific instruments2011

Laser-guided cell micropatterning system.

Russell K Pirlo, Zhen Ma, Andrew Sweeney, Honghai Liu, Julie X Yun, Xiang Peng, Xiaocong Yuan, George X Guo, Bruce Z Gao

Abstract read
In one paragraph

Article in The Review of scientific instruments, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Russell K PirloDepartment of Bioengineering, COMSET, Clemson University, South Carolina 29634, USA.
Zhen Ma
Andrew Sweeney
Honghai Liu
Julie X Yun
Xiang Peng
Xiaocong Yuan
George X Guo
Bruce Z Gao

Funding

Supplement for South Carolina BRIN - 1P20 RR16461P20RR016461 · NCRR · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PIRISI-CREEK, LUCIA AMELIA · 2001 to 2011
$32.3M
UNDERSTANDING AND CONTROLLING TISSUE-SPECIFIC VASCULAR PATTERNINGP20RR021949 · NCRR · CLEMSON UNIVERSITY · PI MARKWALD, ROGER R · 2009 to 2011
$5.2M
Differentiation of Bone-Marrow Stem Cells in a Laser Patterned Myocyte CocultureK25HL088262 · NHLBI · CLEMSON UNIVERSITY · PI GAO, BRUCE Z · 2007 to 2011
$715k
NCRR NIH HHS 2P20RR16461-05NCRR NIH HHS P20 RR016461NCRR NIH HHS P20 RR021949NCRR NIH HHS P20RR021949NHLBI NIH HHS 1K25HL088262-01NHLBI NIH HHS K25 HL088262
6 · The paper itself

Abstract

Employing optical force, our laser-guided cell micropatterning system, is capable of patterning different cell types onto and within standard cell research devices, including commercially available multielectrode arrays (MEAs) with glass culture rings, 35 mm Petri dishes, and microdevices microfabricated with polydimethylsiloxane on 22 mm × 22 mm cover glasses. We discuss the theory of optical forces for generating laser guidance and the calculation of optimal beam characteristics for cell guidance. We describe the hardware design and software program for the cell patterning system. Finally, we demonstrate the capabilities of the system by (1) patterning neurons to form an arbitrary pattern, (2) patterning neurons onto the electrodes of a standard MEA, and (3) patterning and aligning adult cardiomyocytes in a polystyrene Petri dish.

Indexed as

LasersAnimalsCell Culture TechniquesCell ShapeCell SizeElectrodesMyocytes, CardiacNeuronsRats

Identifiers

PMID21280838
PMCPMC3045411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.