Evidence map›Paper›PMID 21279821›Full record

ReviewLangenbeck's archives of surgery2011

Surgical treatment of gastrointestinal neuroendocrine tumors.

Volker Fendrich, Detlef K Bartsch

Abstract readComparative StudyReview
PubMed Publisher
In one paragraph

Review in Langenbeck's archives of surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 82 citations in OpenAlex.

  1. Dual PET Imaging with [Current oncology (Toronto, Ont.) · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. SSAT State-of-the-Art Conference: Current Surgical Management of Gastric Tumors.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2018
    Article
  8. Article
  9. [Surgical approach of gastroduodenal neuroendocrine neoplasms].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2016
    Review
  10. Article
  11. Article
  12. Distal pancreatic resection for neuroendocrine tumors: is laparoscopic really better than open?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2015
    Article
  13. The genetic classification of pancreatic neoplasia.Journal of gastroenterology · 2015
    Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. [Minimally invasive pancreatic tumor surgery : oncological safety and surgical feasibility].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2014
    Review
  19. Laparoscopic resection of pancreatic neuroendocrine tumors.World journal of gastroenterology · 2014
    Review
  20. Zollinger-Ellison syndrome: recent advances and controversies.Current opinion in gastroenterology · 2013
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Volker FendrichDepartment of Surgery, Philipps University Marburg, Baldingerstrasse, Marburg, Germany. fendrich@med.uni-marburg.de
Detlef K Bartsch
Philipps University of Marburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGastroenteropancreatic neuroendocrine tumors (GEP-NETs) are uncommon but clinically challenging and fascinating tumors. GEP-NETs present as either functional or as nonfunctional tumors. Functional tumors are commonly associated with a specific hormonal syndrome directly related to a hormone secreted by the tumor, like gastrinomas with a Zollinger-Ellison syndrome or carcinoid syndrome in patients with neuroendocrine tumors (NET) of the ileum. Nonfunctional tumors do not secrete a hormone resulting in a clinical syndrome.

methodsThe natural course of GEP-NETs is highly variable. Small, benign neoplasms such as 90% of all insulinomas or gastric endocrine tumors type 1 are readily curable by surgical resection; however, most other GEP-NETs have a much less favorable prognosis. Patients with completely resected tumors generally have a good prognosis, and an aggressive surgical approach in patients with advanced disease may also prolong survival.

conclusionsThis review focuses on the current standards of surgical treatment of gastric endocrine tumors, NETs of the pancreas (PNET) and NETs of the ileum. Although the evidence level is low in many instances due to the lack of randomized controlled trials, important treatment recommendations can be given.

Indexed as

Biopsy, NeedleDigestive System Surgical ProceduresFemaleGastrointestinal NeoplasmsHumansImmunohistochemistryMaleNeoplasm InvasivenessNeoplasm StagingNeuroendocrine TumorsPancreatic NeoplasmsPrognosisRisk AssessmentSurvival Analysis

Identifiers

PMID21279821
OpenAlexW2057472730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.