SynthesisInternational journal of colorectal disease2011
Meta-analysis: sacral nerve stimulation versus conservative therapy in the treatment of faecal incontinence.
Synthesis in International journal of colorectal disease, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
French Post-Inscription Study on Sacral Neuromodulation in the Treatment of Fecal Incontinence
The Effect of Platelet Rich Plasma Injection Into the Anal Sphincters on Fecal Incontinence and Quality of Life in Incontinent Patients Had Treated With Low Anterior Resection for Rectal Cancer
Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Is percutaneous tibial nerve stimulation (PTNS) effective for fecal incontinence (FI) in adults compared with sham electrical stimulation? A meta-analysis.Techniques in coloproctology · 2024Pooled it
- Guideline for the diagnosis and treatment of Faecal Incontinence-A UEG/ESCP/ESNM/ESPCG collaboration.United European gastroenterology journal · 2022Guideline
- Systematic review of the impact of sacral neuromodulation on clinical symptoms and gastrointestinal physiology.ANZ journal of surgery · 2016Pooled it
- Sacral nerve stimulation for faecal incontinence and constipation in adults.The Cochrane database of systematic reviews · 2015Pooled it
- Characteristics Associated With Clinically Important Treatment Responses in Women Undergoing Nonsurgical Therapy for Fecal Incontinence.The American journal of gastroenterology · 2020Trial
- Gastric and sacral electrical stimulation for motility disorders-A clinical perspective.Neurogastroenterology and motility · 2025Review
- Patient experience with sacral neuromodulation for faecal incontinence - a multi-centre, longitudinal cohort study.International journal of colorectal disease · 2025Article
- Review
- Long-term Outcomes of Sacral Nerve Stimulation in Pelvic Floor Dysfunctions.International neurourology journal · 2021Article
- Sacral neuromodulation for the prevention of a permanent stoma in patients with severe defecation disorder following intersphincteric resection.Surgery today · 2021Article
- Anorectal angle at rest predicting successful sacral nerve stimulation in idiopathic fecal incontinence-a cohort analysis.International journal of colorectal disease · 2020Article
- Medium-term outcome of percutaneous tibial nerve stimulation in the treatment of fecal incontinence.Techniques in coloproctology · 2018Article
- Treatment possibilities for low anterior resection syndrome: a review of the literature.International journal of colorectal disease · 2018Review
- Evidence-Based Update on Treatments of Fecal Incontinence in Women.Obstetrics and gynecology clinics of North America · 2016Review
- Identifying factors associated with clinical success in patients treated with NASHA(®)/Dx injection for fecal incontinence.Clinical and experimental gastroenterology · 2016Article
- Biofeedback Therapy Before Ileostomy Closure in Patients Undergoing Sphincter-Saving Surgery for Rectal Cancer: A Pilot Study.Annals of coloproctology · 2015Article
- Impact of fecal incontinence and its treatment on quality of life in women.Women's health (London, England) · 2015Review
- Treatment of fecal incontinence: state of the science summary for the National Institute of Diabetes and Digestive and Kidney Diseases workshop.The American journal of gastroenterology · 2015Article
- Current and emerging treatment options for fecal incontinence.Journal of clinical gastroenterology · 2014Review
- A pilot study of chronic pudendal nerve stimulation for faecal incontinence for those who have failed sacral nerve stimulation.Techniques in coloproctology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimSacral nerve stimulation (SNS) has recently been used in the management of faecal incontinence (FI). This study compared SNS to conservative management with regards to functional and quality of life outcomes.
methodsMeta-analysis of studies published between 1995 and 2008 on SNS for FI was performed. Outcomes evaluated were functional, physiological and quality of life. A random-effects model was used and sensitivity analyses performed. Subgroup analyses were performed on age and sphincter status.
resultsThirty-four studies were included, reporting on 944 patients undergoing peripheral nerve evaluation; 665 underwent permanent SNS. Weekly incontinence episodes (weighted mean difference [WMD] -6.83; 95% confidence intervals [CI] -8.05, -5.60; p < 0.001) and incontinence scores (WMD -10.57; 95% CI -11.89, -9.24; p < 0.001) were significantly reduced with SNS; ability to defer defecation (WMD 7.99 min; 95% CI 5.93, 10.05; p < 0.001) was increased. Most SF-36 and FIQL domains improved following SNS, and mean anal pressures increased significantly (p < 0.001). Results remained consistent on sensitivity analysis. The under-56 years age group showed smaller functional but greater physiological and quality of life improvements. Results were similar between sphincter intact and impaired subgroups. The complication rate was 15% for permanent SNS, with 3% resulting in permanent explantation.
conclusionSNS results in significant improvements in objective and subjective measures for faecally incontinent patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.