ReviewWiley interdisciplinary reviews. RNA
Alternative mRNA polyadenylation in eukaryotes: an effective regulator of gene expression.
Review in Wiley interdisciplinary reviews. RNA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 144 citations in OpenAlex.
- Nucleotide-resolution Mapping of RNA N6-Methyladenosine (m6A) modifications and comprehensive analysis of global polyadenylation events in mRNA 3' end processing in malaria pathogenbioRxiv : the preprint server for biology · 2025Article
- High-Level Production of a Recombinant Protein inInternational journal of molecular sciences · 2024Article
- mMolecular therapy. Nucleic acids · 2022Article
- Alternative splicing and alternative polyadenylation define tumor immune microenvironment and pharmacogenomic landscape in clear cell renal carcinoma.Molecular therapy. Nucleic acids · 2022Article
- Alternative Polyadenylation and Salicylic Acid Modulate Root Responses to Low Nitrogen Availability.Plants (Basel, Switzerland) · 2020Article
- Tissue-specific mechanisms of alternative polyadenylation: Testis, brain, and beyond (2018 update).Wiley interdisciplinary reviews. RNA · 2019Review
- Characterization of mRNA polyadenylation in the apicomplexa.PloS one · 2018Article
- Distinct regulation of alternative polyadenylation and gene expression by nuclear poly(A) polymerases.Nucleic acids research · 2017Article
- Evidence that a threshold of serine/arginine-rich (SR) proteins recruits CFIm to promote rous sarcoma virus mRNA 3' end formation.Virology · 2016Article
- Natural antisense RNA promotes 3' end processing and maturation of MALAT1 lncRNA.Nucleic acids research · 2016Article
- Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2.Molecular cell · 2016Article
- Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control.BMC biology · 2016Article
- The Cstf2t Polyadenylation Gene Plays a Sex-Specific Role in Learning Behaviors in Mice.PloS one · 2016Article
- Intronic cleavage and polyadenylation regulates gene expression during DNA damage response through U1 snRNA.Cell discovery · 2016Article
- Plasma cell formation, secretion, and persistence: the short and the long of it.Critical reviews in immunology · 2014Review
- Article
- DNA damage induces targeted, genome-wide variation of poly(A) sites in budding yeast.Genome research · 2013Article
- Alternative pre-mRNA splicing in neurons: growing up and extending its reach.Trends in genetics : TIG · 2013Review
- Analysis of alternative cleavage and polyadenylation by 3' region extraction and deep sequencing.Nature methods · 2013Article
- Cleavage and polyadenylation specificity factor 1 (CPSF1) regulates alternative splicing of interleukin 7 receptor (IL7R) exon 6.RNA (New York, N.Y.) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Alternative RNA processing mechanisms, including alternative splicing and alternative polyadenylation, are increasingly recognized as important regulators of gene expression. This article will focus on what has recently been described about alternative polyadenylation in development, differentiation, and disease in higher eukaryotes. We will also describe how the evolving global methodologies for examining the cellular transcriptome, both experimental and bioinformatic, are revealing new details about the complex nature of alternative 3' end formation, as well as interactions with other RNA-mediated and RNA processing mechanisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.