ArticleAnnual ORNL Biomedical Science and Engineering Center Conference. ORNL Biomedical Science and Engineering Center Conference2009
Cell Free Translation in Engineered Picoliter Volume Containers.
Article in Annual ORNL Biomedical Science and Engineering Center Conference. ORNL Biomedical Science and Engineering Center Conference, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- "Basicles": Microbial Growth and Production Monitoring in Giant Lipid Vesicles.ACS applied materials & interfaces · 2019Article
- Fabrication of nanoporous membranes for tuning microbial interactions and biochemical reactions.Journal of vacuum science and technology. B, Nanotechnology & microelectronics : materials, processing, measurement, & phenomena : JVST B · 2015Article
- Microreactor array device.Scientific reports · 2015Article
- Thrombin-mediated transcriptional regulation using DNA aptamers in DNA-based cell-free protein synthesis.ACS synthetic biology · 2014Article
- Remotely activated protein-producing nanoparticles.Nano letters · 2012Article
- Enzyme reactions in nanoporous, picoliter volume containers.Analytical chemistry · 2012Article
- Model for biological communication in a nanofabricated cell-mimic driven by stochastic resonance.Nano communication networks · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Engineers seek to use biological design principles to manipulate information and import new functionality to synthetic devices. Such devices inspired by natural systems could, in turn, play a crucial role in allowing biologists to explore the effects of physical transport and extreme conditions of temperature and pH on reaction systems. For example, engineered reaction containers can be physically and chemically defined to control the flux of molecules of different sizes and charge. The design and testing of such a container is described here. It has a volume of 19pL with defined slits of 200nm. The device successfully contained DNA and protein molecules and is evaluated for carrying out cell-free protein synthesis. The effect of DNA concentration and slit size on protein yield is discussed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.