ArticleKidney international2011
Raging hormones: gender and renal disease.
Article in Kidney international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Derivation and Validation of a Prediction Model of End-Stage Renal Disease in Patients With Type 2 Diabetes Based on a Systematic Review and Meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats.American journal of physiology. Renal physiology · 2023Article
- Does sex interact with the 2D:4D ratio or adult circulating hormones on the estimated glomerular filtration rate? A cross-sectional study in Ghana.Physiological reports · 2022Article
- The SSAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Sex differences in redox homeostasis in renal disease.Redox biology · 2020Review
- Article
- Sex and the kidneys: current understanding and research opportunities.Nature reviews. Nephrology · 2019Review
- Sex-Related Disparities in CKD Progression.Journal of the American Society of Nephrology : JASN · 2019Observational
- Sex Differences in Renal Inflammation and Injury in High-Fat Diet-Fed Dahl Salt-Sensitive Rats.Hypertension (Dallas, Tex. : 1979) · 2018Article
- Serum uromodulin-a marker of kidney function and renal parenchymal integrity.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2018Article
- Sex differences in transplantation.Transplantation reviews (Orlando, Fla.) · 2017Review
- Is Testosterone Detrimental to Renal Function?Kidney international reports · 2016Article
- Estrogen preserves split renal function in a chronic complete unilateral ureteral obstruction animal model.Experimental and therapeutic medicine · 2014Article
- Androgen-STAT3 activation may contribute to gender disparity in human simply renal cysts.International journal of clinical and experimental pathology · 2013Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gender affects the progression of renal disease. In a variety of animal models and in certain human renal diseases, females exhibit a more modest course of kidney disease. Estrogens and testosterone have been implicated in this gender disparity. Doublier and colleagues explore the direct effects of sex hormones on podocyte viability in the α-estrogen receptor knockout (αERKO) mouse. They report that testosterone induces, and estradiol inhibits, podocyte damage in this model.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.