ReviewCellular & molecular immunology2011
Celiac disease: diagnostic criteria in progress.
Review in Cellular & molecular immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 130 citations in OpenAlex.
- Article
- Delayed Bone Age and Osteoprotegerin Levels in Pediatric Celiac Disease: A Three-Year Case-Control Study.Nutrients · 2025Article
- Utilizing Telemedicine Applications in Celiac Disease and Other Gluten-Free-Diet-Dependent Conditions: Insights from the COVID-19 Pandemic.Healthcare (Basel, Switzerland) · 2024Review
- Genetic, Immunological, Dietary, Gut Microbiota, and Environmental Determinants of Osteoporosis in the Course of Celiac Disease: Which Factor Plays the First Violin in This Orchestra?Calcified tissue international · 2024Review
- From an understanding of etiopathogenesis to novel therapies-what is new in the treatment of celiac disease?Frontiers in pharmacology · 2024Review
- Rectal prolapse as a manifestation of inflammatory bowel disease with celiac disease in a 2-year-old male: a rare case report.Annals of medicine and surgery (2012) · 2023Article
- [29/f-Abdominal pain, distended abdomen and occasionally diarrhea : Preparation for the medical specialist examination: part 120].Der Internist · 2022Article
- Diagnosing and Monitoring Celiac Patients with Selective IgA Deficiency: Still an Open Issue.Digestive diseases and sciences · 2021Review
- Wheat/Gluten-Related Disorders and Gluten-Free Diet Misconceptions: A Review.Foods (Basel, Switzerland) · 2021Review
- Value of biopsy in a cohort of children with high-titer celiac serologies: observation of dynamic policy differences between Europe and North America.BMC health services research · 2020Observational
- Predictive Factors and Clinical Impact of Deep Remission in Celiac Disease.GE Portuguese journal of gastroenterology · 2020Article
- Celiac disease: a comprehensive current review.BMC medicine · 2019Review
- Nonceliac Wheat Sensitivity: An Immune-Mediated Condition with Systemic Manifestations.Gastroenterology clinics of North America · 2019Review
- Case Report: Rare comorbidity of celiac disease and Evans syndrome: The rare correlation of Celiac and Evans syndrome.F1000Research · 2019Article
- Transient Periictal Brain Imaging Abnormality in a Saudi Patient with Probable Celiac Disease Epilepsy and Occipital Calcification Syndrome.Case reports in neurological medicine · 2019Article
- Novel screening test for celiac disease using peptide functionalised gold nanoparticles.World journal of gastroenterology · 2018Article
- Skin and coeliac disease, a lot to think about: a case series.BMJ case reports · 2018Article
- Next-Generation Autoantibody Testing by Combination of Screening and Confirmation-the CytoBead® Technology.Clinical reviews in allergy & immunology · 2017Review
- The Autoimmunity's Footprint in Pediatrics: Type 1 Diabetes, Coeliac Disease, Thyroiditis.Maedica · 2017Article
- Celiac disease: From pathophysiology to treatment.World journal of gastrointestinal pathophysiology · 2017Review
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Until a few years ago, celiac disease (CD) was thought to be a rare food intolerance that was confined to childhood and characterized by severe malabsorption and flat intestinal mucosa. Currently, CD is regarded as an autoimmune disorder that is common in the general population (affecting 1 in 100 individuals), with possible onset at any age and with many possible presentations. The identification of CD is challenging because it can begin not only with diarrhea and weight loss but also with atypical gastrointestinal (constipation and recurrent abdominal pain) and extra-intestinal symptoms (anemia, raised transaminases, osteoporosis, recurrent miscarriages, aphthous stomatitis and associated autoimmune disorders), or it could be completely symptomless. Over the last 20 years, the diagnostic accuracy of serology for CD has progressively increased with the development of highly reliable tests, such as the detection of IgA tissue transglutaminase and antiendomysial and IgG antideamidated gliadin peptide antibodies. The routine use of antibody markers has allowed researchers to discover a very high number of 'borderline' cases, characterized by positive serology and mild intestinal lesions or normal small intestine architecture, which can be classified as potential CD. Therefore, it is evident that the 'old celiac disease' with flat mucosa is only a part of the spectrum of CD. It is possible that serology could identify CD in its early stages, before the appearance of severe intestinal damage. In cases with a positive serology but with mild or absent intestinal lesions, the detection of HLA-DQ2 and HLA-DQ8 can help reinforce or exclude the diagnosis of gluten sensitivity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.