ArticleNature methods2011
Five challenges to bringing single-molecule force spectroscopy into living cells.
Article in Nature methods, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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Who cites it
44 citing papers in PubMed.
- Exploring force-driven stochastic folding dynamics in mechano-responsive proteins and implications in phenotypic variation.Nature communications · 2025Article
- S373P Mutation Stabilizes the Receptor-Binding Domain of the Spike Protein in Omicron and Promotes Binding.JACS Au · 2023Article
- The glycocalyx affects the mechanotransductive perception of the topographical microenvironment.Journal of nanobiotechnology · 2022Article
- Massively Parallelized Molecular Force Manipulation with On-Demand Thermal and Optical Control.Journal of the American Chemical Society · 2021Article
- Article
- Biochemistry: one molecule at a time.Essays in biochemistry · 2021Article
- DNA replication machinery: Insights fromComputational and structural biotechnology journal · 2021Review
- Next Generation Methods for Single-Molecule Force Spectroscopy on Polyproteins and Receptor-Ligand Complexes.Frontiers in molecular biosciences · 2020Review
- Mechanotransduction in neuronal cell development and functioning.Biophysical reviews · 2019Review
- Force Spectroscopy and Beyond: Innovations and Opportunities.Biophysical journal · 2018Review
- Characterization of the mechanical properties of cancer cells in 3D matrices in response to collagen concentration and cytoskeletal inhibitors.Integrative biology : quantitative biosciences from nano to macro · 2018Article
- Magnetic Nanotweezers for Interrogating Biological Processes in Space and Time.Accounts of chemical research · 2018Review
- Light-Responsive Polymer Particles as Force Clamps for the Mechanical Unfolding of Target Molecules.Nano letters · 2018Article
- High-speed atomic force microscopy and its future prospects.Biophysical reviews · 2018Review
- Analyzing the micromechanics of the cell division apparatus.Methods in cell biology · 2018Article
- Multiplexed fluctuation-dissipation-theorem calibration of optical tweezers inside living cells.The Review of scientific instruments · 2017Article
- Single-cell mechanogenetics using monovalent magnetoplasmonic nanoparticles.Nature protocols · 2017Article
- Photothermally triggered actuation of hybrid materials as a new platform for in vitro cell manipulation.Nature communications · 2017Article
- Imaging and Force Recognition of Single Molecular Behaviors Using Atomic Force Microscopy.Sensors (Basel, Switzerland) · 2017Review
- Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, single-molecule force spectroscopy techniques have been used to study how inter- and intramolecular interactions control the assembly and functional state of biomolecular machinery in vitro. Here we discuss the problems and challenges that need to be addressed to bring these technologies into living cells and to learn how cellular machinery is controlled in vivo.
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21278722What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.