ReviewHearing research2011
Complex primary afferents: What the distribution of electrophysiologically-relevant phenotypes within the spiral ganglion tells us about peripheral neural coding.
Review in Hearing research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Noise-invariant representations of sound emerge along the canonical cortical hierarchy.PLoS biology · 2026Article
- Dopaminergic modulation of low- and high-spontaneous rate type I auditory nerve fiber activity.Journal of neurophysiology · 2026Article
- A modiolar-pillar gradient in auditory-nerve dendritic length: A novel post-synaptic contribution to dynamic range?Hearing research · 2025Article
- Molecular signatures define subtypes of auditory afferents with distinct peripheral projection patterns and physiological properties.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Patch-clamp Recordings and Single Fiber Labeling from Spiral Ganglion Somata in Acutely Prepared Semi-intact Cochleae from Neonatal Rats.Bio-protocol · 2022Article
- A combined genome-wide association and molecular study of age-related hearing loss in H. sapiens.BMC medicine · 2021Article
- Single-Cell RNA Analysis of Type I Spiral Ganglion Neurons Reveals aFrontiers in molecular neuroscience · 2020Article
- Hair Cell Afferent Synapses: Function and Dysfunction.Cold Spring Harbor perspectives in medicine · 2019Review
- Otoprotective Effects of Stephania tetrandra S. Moore Herb Isolate against Acoustic Trauma.Journal of the Association for Research in Otolaryngology : JARO · 2018Article
- Concomitant differentiation of a population of mouse embryonic stem cells into neuron-like cells and schwann cell-like cells in a slow-flow microfluidic device.Developmental dynamics : an official publication of the American Association of Anatomists · 2017Article
- Single-Cell Transcriptome Analysis of Developing and Regenerating Spiral Ganglion Neurons.Current pharmacology reports · 2016Article
- Decreased Speech-In-Noise Understanding in Young Adults with Tinnitus.Frontiers in neuroscience · 2016Article
- Quantitative analysis linking inner hair cell voltage changes and postsynaptic conductance change: a modelling study.BioMed research international · 2015Article
- Heterogeneous intrinsic excitability of murine spiral ganglion neurons is determined by Kv1 and HCN channels.Neuroscience · 2014Article
- Association of the Kv1 family of K+ channels and their functional blueprint in the properties of auditory neurons as revealed by genetic and functional analyses.Journal of neurophysiology · 2013Article
- Glial cell line-derived neurotrophic factor (GDNF) induces neuritogenesis in the cochlear spiral ganglion via neural cell adhesion molecule (NCAM).Molecular and cellular neurosciences · 2013Article
- Developmental changes in the responsiveness of rat spiral ganglion neurons to neurotrophic factors in dissociated culture: differential responses for survival, neuritogenesis and neuronal morphology.Cell and tissue research · 2013Article
- The use of neurotrophin therapy in the inner ear to augment cochlear implantation outcomes.Anatomical record (Hoboken, N.J. : 2007) · 2012Review
- Developmental gene expression profiling along the tonotopic axis of the mouse cochlea.PloS one · 2012Article
- Complex distribution patterns of voltage-gated calcium channel α-subunits in the spiral ganglion.Hearing research · 2011Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Spiral ganglion neurons are the first neural element of the auditory system. They receive precise synaptic signals which represent features of sound stimuli encoded by hair cell receptors and they deliver a digital representation of this information to the central nervous system. It is well known that spiral ganglion neurons are selectively responsive to specific sound frequencies, and that numerous structural and physiological specializations in the inner ear increase the quality of this tuning, beyond what could be accomplished by the passive properties of the basilar membrane. Further, consistent with what we know about other sensory systems, it is becoming clear that the parallel divergent innervation pattern of type I spiral ganglion neurons has the potential to encode additional features of sound stimuli. To date, we understand the most about the sub-modalities of frequency and intensity coding in the peripheral auditory system. Work reviewed herein will address the issue of how intrinsic electrophysiological features of the neurons themselves have the potential to contribute to the precision of coding and transmitting information about these two parameters to higher auditory centers for further processing.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.