Evidence map›Paper›PMID 21276837›Full record

ReviewBiochimica et biophysica acta2011

Biochemical effects of ozone on asthma during postnatal development.

Richard L Auten, W Michael Foster

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Ozone in the Development of Pediatric Asthma and Atopic Disease.Immunology and allergy clinics of North America · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Richard L AutenDepartment of Pediatrics (Neonatal Medicine), Duke University, DUMC Box 3373, Durham, NC 27710, USA. auten@duke.edu
W Michael Foster
Duke Medical Center · USDuke University · US

Funding

Surfactant Protein-A Regulation of Innate Immunityin AsthmaP01AI081672 · NIAID · DUKE UNIVERSITY · PI QUE, LORETTA G · 2009 to 2013
$7.4M
NIAID NIH HHS AI 081672NIAID NIH HHS P01 AI081672
6 · The paper itself

Abstract

backgroundOzone exposure during early life has the potential to contribute to the development of asthma as well as to exacerbate underlying allergic asthma. SCOPE OF REVIEW: Developmentally regulated aspects of sensitivity to ozone exposure and downstream biochemical and cellular responses. MAJOR

conclusionsDevelopmental differences in antioxidant defense responses, respiratory physiology, and vulnerabilities to cellular injury during particular developmental stages all contribute to disparities in the health effects of ozone exposure between children and adults. GENERAL SIGNIFICANCE: Ozone exposure has the capacity to affect multiple aspects of the "effector arc" of airway hyperresponsiveness, ranging from initial epithelial damage and neural excitation to neural reprogramming during infancy. This article is part of a Special Issue entitled: Biochemistry of Asthma.

Indexed as

AsthmaChildChild DevelopmentHumansLungNeuronal PlasticityNitric OxideOxidative StressOzoneNitric OxideOzone

Identifiers

PMID21276837
PMCPMC3106122
OpenAlexW2066387493

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.