Evidence map›Paper›PMID 21276709›Full record

ReviewAnnals of vascular surgery2011

Current usage and future directions for the bovine pericardial patch.

Xin Li, Yuanyuan Guo, Kenneth R Ziegler, Lynn S Model, Sammy D D Eghbalieh, Robert A Brenes, Susun T Kim, Chang Shu, Alan Dardik

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Annals of vascular surgery, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05661981 (A Post Market Multicenter Clinical Investigation of GLYCAR Bovine Pericardial Patch With EnCap™ Technology in Cardiac and Vascular Repair or Reconstruction Surgery. GLYCAR Study), which is not on this map. Cited by 70 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05661981 active not recruitingnot on this mapstarted 2023, after this paper: background citation

A Post Market Multicenter Clinical Investigation of GLYCAR Bovine Pericardial Patch With EnCap™ Technology in Cardiac and Vascular Repair or Reconstruction Surgery. GLYCAR Study

TypeobservationalSponsorGLYCAR SA (Pty) LtdRan2023 to 2027Enrolled110ConditionsCongenital Premature Cardiac Closure, Cardiac and Great Vessel Reconstruction and Repair, Peripheral Vascular Reconstruction and RepairArmsGLYCAR Pericardial Patch
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 1 synthesis or guideline pooled it, 182 citations in OpenAlex.

  1. Pooled it
  2. Article
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  12. Review
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  14. Review
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  17. Progress in the application of patch materials in cardiovascular surgery.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2023
    Article
  18. Article
  19. Article
  20. Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Xin LiDepartment of Surgery, Yale University School of Medicine, New Haven, CT, USA.
Yuanyuan Guo
Kenneth R Ziegler
Lynn S Model
Sammy D D Eghbalieh
Robert A Brenes
Susun T Kim
Chang Shu
Alan Dardik
Yale University · USCentral South University · CNSt Mary's Hospital · USVA Connecticut Healthcare System · US

Funding

Research Training in AnesthesiaT32GM086287 · NIGMS · YALE UNIVERSITY · PI ROBERT SCHONBERGER · 2009 to 2026
$3.7M
Molecular Regulation of Vein Graft AdapationR01HL095498 · NHLBI · YALE UNIVERSITY · PI DARDIK, ALAN · 2009 to 2013
$2.4M
NHLBI NIH HHS R01 HL095498NHLBI NIH HHS R01-HL095498-01
6 · The paper itself

Abstract

Bovine pericardium (BP) is widely used in surgery and is commonly used as a patch after arteriotomy in cardiovascular surgery. BP patches have several advantages compared with prosthetic patches, including superior biocompatability, easy handling, less suture line bleeding, and possibly reduced rates of infection. These advantages of BP have led to its common use during carotid endarterectomy (CEA). However, long-term clinical results reported after CEA have suggested several issues that may be related to the patch, including restenosis, pseudoaneurysm formation, infection, fibrosis, calcification, and thrombosis. These complications may diminish the long-term efficacy of CEA and suggest potential areas for improvement of surgical patches. Understanding the mechanisms by which BP heals after patch angioplasty may lead to next generation tissue-engineered patches.

Indexed as

Biocompatible MaterialsAnimalsCardiac Surgical ProceduresCardiovascular DiseasesCattleEndarterectomy, CarotidHumansPericardiumTreatment OutcomeVascular Surgical ProceduresWound HealingBiocompatible Materials

Identifiers

PMID21276709
PMCPMC3085588
OpenAlexW2107086407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.