ArticleBMC genomics2011
Population transcriptomics of Drosophila melanogaster females.
Article in BMC genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed, 51 citations in OpenAlex.
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- Experimental evolution-induced transcriptome and phenotype responses of Drosophila melanogaster to novel thermal environments.The Journal of experimental biology · 2025Article
- Dichotomous transcriptome divergence at the cell-type level between thebioRxiv : the preprint server for biology · 2025Article
- Sensitivity of transcriptomics: Different samples and methodology alter conclusions in Gulf pipefish (Syngnathus scovelli).The Journal of heredity · 2025Article
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- Selection and geography shape male reproductive tract transcriptomes in Drosophila melanogaster.Genetics · 2023Article
- Natural variation in the maternal and zygotic mRNA complements of the early embryo in Drosophila melanogaster.BMC genomics · 2022Article
- Intraspecific Transcriptome Variation and Sex-Biased Expression in Anopheles arabiensis.Genome biology and evolution · 2021Article
- Parallel and population-specific gene regulatory evolution in cold-adapted fly populations.Genetics · 2021Article
- Transcriptome analysis ofEcology and evolution · 2020Article
- Population Genetic and Functional Analysis of aGenes · 2019Article
- Article
- Genome-wide patterns of local adaptation in Western European Drosophila melanogaster natural populations.Scientific reports · 2018Article
- Genetic constraints on microevolutionary divergence of sex-biased gene expression.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Article
- Gene Regulatory Variation inGenetics · 2018Article
- Functional characterization of adaptive variation within a cis-regulatory element influencing Drosophila melanogaster growth.PLoS biology · 2018Article
- TEtools facilitates big data expression analysis of transposable elements and reveals an antagonism between their activity and that of piRNA genes.Nucleic acids research · 2017Article
- Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster.BMC genomics · 2016Article
- Canalization of gene expression is a major signature of regulatory cold adaptation in temperate Drosophila melanogaster.BMC genomics · 2016Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVariation at the level of gene expression is abundant in natural populations and is thought to contribute to the adaptive divergence of populations and species. Gene expression also differs considerably between males and females. Here we report a microarray analysis of gene expression variation among females of 16 Drosophila melanogaster strains derived from natural populations, including eight strains from the putative ancestral range in sub-Saharan Africa and eight strains from Europe. Gene expression variation among males of the same strains was reported previously.
resultsWe detected relatively low levels of expression polymorphism within populations, but much higher expression divergence between populations. A total of 569 genes showed a significant expression difference between the African and European populations at a false discovery rate of 5%. Genes with significant over-expression in Europe included the insecticide resistance gene Cyp6g1, as well as genes involved in proteolysis and olfaction. Genes with functions in carbohydrate metabolism and vision were significantly over-expressed in the African population. There was little overlap between genes expressed differently between populations in females and males.
conclusionsOur results suggest that adaptive changes in gene expression have accompanied the out-of-Africa migration of D. melanogaster. Comparison of female and male expression data indicates that the vast majority of genes differing in expression between populations do so in only one sex and suggests that most regulatory adaptation has been sex-specific.
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