Evidence map›Paper›PMID 21274756›Full record

ReviewCurrent hypertension reports2011

Metabolic syndrome, androgens, and hypertension.

Mohadetheh Moulana, Roberta Lima, Jane F Reckelhoff

Open access · greenAbstract readReview
In one paragraph

Review in Current hypertension reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  12. Article
  13. Sperm impairing microbial factor: potential candidate for male contraception.Reproductive biology and endocrinology : RB&E · 2020
    Article
  14. Review
  15. Hypertension and Reproduction.Current hypertension reports · 2020
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Androgen receptor in human endothelial cells.The Journal of endocrinology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Mohadetheh MoulanaWomen's Health Research Center, University of Mississippi Medical Center, 2500 N. State Street, Jackson, MS 39216-4505, USA.
Roberta Lima
Jane F Reckelhoff
University of Mississippi Medical Center · USState Street (United States) · US

Funding

STRUCTURAL VASCULAR ADAPTATION OF THE MICROCIRCULATIONP01HL051971 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI HALL, JOHN E · 1993 to 2018
$39.4M
HUMORAL FACTORS IN GENDER DIFFERENCES IN BP CONTROLR01HL066072 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 2001 to 2015
$3.9M
Gender and susceptibility to kidney damage in high BP.R01HL069194 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 2001 to 2010
$2.5M
NHLBI NIH HHS P01 HL051971NHLBI NIH HHS P01 HL51971NHLBI NIH HHS R01 HL066072NHLBI NIH HHS R01 HL069194NHLBI NIH HHS R01 HL66072NHLBI NIH HHS R01 HL69194
6 · The paper itself

Abstract

Obesity is one of the constellation of factors that make up the definition of the metabolic syndrome. Metabolic syndrome is also associated with insulin resistance, dyslipidemia, hypertriglyceridemia, and type 2 diabetes mellitus. The presence of obesity and metabolic syndrome in men and women is also associated with increased risk of cardiovascular disease and hypertension. In men, obesity and metabolic syndrome are associated with reductions in testosterone levels. In women, obesity and metabolic syndrome are associated with increases in androgen levels. In men, reductions in androgen levels are associated with inflammation, and androgen supplements reduce inflammation. In women, increases in androgens are associated with increases in inflammatory cytokines, and reducing androgens reduces inflammation. This review discusses the possibility that the effects of androgens on metabolic syndrome and its sequelae may differ between males and females.

Indexed as

AndrogensFemaleHumansHypertensionMaleMetabolic SyndromeObesityAndrogens

Identifiers

PMID21274756
PMCPMC3820276
OpenAlexW2075318706

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.