Trial reportPsychopharmacology2011
An acute psychosocial stressor increases drinking in non-treatment-seeking alcoholics.
Trial report in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- A systematic review with meta-analysis on the relation between acute stress, alcohol consumption and cortisol levels in individuals with a personal, familial or no alcohol use disorder.Translational psychiatry · 2025Pooled it
- A meta-analytic review of the effectiveness of mood inductions in eliciting emotion-based behavioral risk-taking and craving in the laboratory.Emotion (Washington, D.C.) · 2023Pooled it
- The effect of laboratory manipulations of negative affect on alcohol craving and use: A meta-analysis.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2018Pooled it
- Alcohol craving under stress in healthy young men: A randomized laboratory study.Alcohol, clinical & experimental research · 2026Trial
- Acute stress increases ad-libitum alcohol consumption in heavy drinkers, but not through impaired inhibitory control.Psychopharmacology · 2016Trial
- Yohimbine increases opioid-seeking behavior in heroin-dependent, buprenorphine-maintained individuals.Psychopharmacology · 2013Trial
- BLA kappa opioid receptor inputs to the BNST mediate social stress-induced increases in alcohol drinking.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Behavioral Impaired Control over Alcohol: Comparing Self-Medication and Behavioral Economic Models with the Interacting Effects of Acute Stress, Chronic Stress with Physical Neglect History, and Sex Assigned at Birth.Behavioral sciences (Basel, Switzerland) · 2026Article
- BLAbioRxiv : the preprint server for biology · 2024Article
- Contextual and psychosocial factors influencing drug reward in humans: The importance of non-drug reinforcement.Pharmacology, biochemistry, and behavior · 2024Review
- Brain correlates and functional connectivity linking stress, autonomic dysregulation, and alcohol motivation.Neurobiology of stress · 2024Article
- The ad-libitum taste test as measure of momentary alcohol use in the laboratory: an investigation of construct validity and confounding factors.Psychopharmacology · 2024Article
- Does loneliness before the age of twelve indirectly affect impaired control over drinking, alcohol use, and problems through perceived stress?Addictive behaviors reports · 2022Article
- What is behind the lifestyle risk factors for head and neck cancer?Frontiers in psychology · 2022Review
- Hypoactive Thalamic Crh+ Cells in a Female Mouse Model of Alcohol Drinking After Social Trauma.Biological psychiatry · 2021Article
- Translational opportunities in animal and human models to study alcohol use disorder.Translational psychiatry · 2021Review
- Longitudinal patterns of momentary stress during outpatient opioid agonist treatment: A growth-mixture-model approach to classifying patients.Drug and alcohol dependence · 2021Article
- Associations of subjective and objective stress responses with interpersonal trauma, PTSD, stress-induced drinking, and drinking to cope in young adults.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2021Article
- Effect of Coronavirus Disease 2019 on the Psychology and Behavior of Patients on Methadone Maintenance Treatment in Wuhan, China: A Clinical Observational Study.Frontiers in psychiatry · 2021Article
- Mobile alcohol biosensors and pharmacotherapy development research.Alcohol (Fayetteville, N.Y.) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
rationaleAlthough studies suggest that stress is an important reason for relapse in alcoholics, few controlled studies have been conducted to examine this assumption. Evidence of stress-potentiated drinking would substantiate this clinical observation and would contribute to the development of a model that would be valuable to alcohol treatment research.
objectivesThe hypothesis was tested that an acute psychosocial stressor, the Trier Social Stress Test (TSST), increases alcohol consumption in non-treatment-seeking alcoholics.
methodsSeventy-nine alcohol-dependent participants (40 women) were randomly assigned to receive the TSST or a no-stress condition. Immediately afterward, all participants received an initial dose of their preferred alcoholic beverage to achieve a target blood alcohol concentration of 0.03 g/dl (to prime subsequent drinking in the laboratory). Participants then participated in a mock taste test of two glasses of beer. Primary dependent measures were whether s/he drank all of the beer available (yes/no) and total amount of beer consumed (milliliters).
resultsStressed participants were twice as likely as non-stressed participants to drink all of the beer available, a significant effect. Although the stressed group drank more milliliters than the non-stressed group, this effect failed to reach significance, likely due to ceiling effects. There were no significant stress group × gender effects on either outcome.
conclusionsThis study supports that stress-potentiated drinking is valid and can be modeled in a clinical laboratory setting.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.