ArticlePsychopharmacology2011
Exploring the relationship between vitamin D and basic personality traits.
Article in Psychopharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 28 citations in OpenAlex.
- Effect of vitamin D treatment in children with attention-deficit hyperactivity disorder.World journal of pediatrics : WJP · 2019Trial
- The mediating role of Vitamin D in the association between personality and memory: Evidence from two samples.Biological psychology · 2023Article
- Mental depression: Relation to different disease status, newer treatments and its association with COVID-19 pandemic (Review).Molecular medicine reports · 2021Review
- Vitamin D polygenic score is associated with neuroticism and the general psychopathology factor.Progress in neuro-psychopharmacology & biological psychiatry · 2020Article
- Association of vitamin D nutrition with neuro-developmental outcome of infants of slums in Bangladesh.PloS one · 2019Observational
- 1,25(OH)2D3 dependent overt hyperactivity phenotype in klotho-hypomorphic mice.Scientific reports · 2016Article
- The association of 25-hydroxyvitamin D3 and D2 with behavioural problems in childhood.PloS one · 2012Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
rationaleSeveral studies suggest an association between hypovitaminosis D and basic and executive cognitive functions, depression, bipolar disorder, and schizophrenia. A recent study confirms neophobic responses in vitamin D receptor mutant mice. We explored whether the plasma levels of 1,25-dihydroxyvitamin D (1,25(OH)(2)D(3)), the active form of vitamin D, are correlated with basic personality traits.
methodsA total of 206 healthy unrelated volunteers (108 male, 98 female, age 31 ± 13 years) completed the German version of the NEO Five-Factor Inventory (NEO-FFI), which allows reliable and valid assessment of personality along the dimensions neuroticism, extraversion, openness to new experiences, agreeableness and conscientiousness.
resultsWe found a significant correlation between 1,25(OH)(2)D(3) concentration and the factor extraversion (n = 206, r = 0.202, p = 0.004) and the factor openness (n = 206, r = 0.148, p = 0.034).
conclusionThe possible mechanisms by which 1,25(OH)(2)D(3) acts on the brain might include Ca(2+) signaling, buffering antioxidant, and anti-inflammatory defenses against vascular injury, stimulating neurotrophins and improving metabolic and cardiovascular function. In conclusion, we suggest that 1,25(OH)(2)D(3) might influence personality traits, promoting extrovert and open behavior.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.