Evidence map›Paper›PMID 21274478›Full record

ArticleThe Analyst2011

Thermoplastic microfluidic devices and their applications in protein and DNA analysis.

Ke Liu, Z Hugh Fan

Abstract read
In one paragraph

Article in The Analyst, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 70 citations in OpenAlex.

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  17. Enhanced Detection of Single Viruses On-Chip via Hydrodynamic Focusing.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ke LiuInterdisciplinary Microsystems Group, Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida 32611-6250, USA.
Z Hugh Fan
University of Florida · US

Funding

Two-Dimensional Electrophoresis Device for Biomarker DetectionR21RR024397 · NCRR · UNIVERSITY OF FLORIDA · PI FAN, Z. HUGH · 2009 to 2010
$535k
NCRR NIH HHS R21 RR024397NCRR NIH HHS R21RR024397
6 · The paper itself

Abstract

Microfluidics is a platform technology that has been used for genomics, proteomics, chemical synthesis, environment monitoring, cellular studies, and other applications. The fabrication materials of microfluidic devices have traditionally included silicon and glass, but plastics have gained increasing attention in the past few years. We focus this review on thermoplastic microfluidic devices and their applications in protein and DNA analysis. We outline the device design and fabrication methods, followed by discussion on the strategies of surface treatment. We then concentrate on several significant advancements in applying thermoplastic microfluidic devices to protein separation, immunoassays, and DNA analysis. Comparison among numerous efforts, as well as the discussion on the challenges and innovation associated with detection, is presented.

Indexed as

DNAImmunoassayMicroarray AnalysisMicrofluidic Analytical TechniquesPlasticsProteinsSurface PropertiesDNAPlasticsProteins

Identifiers

PMID21274478
PMCPMC3596791
OpenAlexW1990386579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.