ArticleAdvances in urology2011
Procalcitonin: a key marker in children with urinary tract infection.
Article in Advances in urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The value of procalcitonin and urinary NGAL in the prediction of acute pyelonephritis and kidney scarring in pediatric patients with a history of febrile urinary tract infection: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- A new point-of-care test for the rapid antimicrobial susceptibility assessment of uropathogens.PloS one · 2023Trial
- Biomarkers and Their Association with Kidney Scarring After the First Episode of Febrile Urinary Tract Infection or Vesicoureteral Reflux in Pediatric Patients.Medicina (Kaunas, Lithuania) · 2026Article
- Efficacy of Interleukin 8 (IL-8) in the detection of urinary tract infection.Frontiers in immunology · 2026Article
- Evidence-Informed Practice: Diagnostic Questions in Urinary Tract Infections in the Elderly.The western journal of emergency medicine · 2019Review
- A Putative Role of Apolipoprotein L1 Polymorphism in Renal Parenchymal Scarring Following Febrile Urinary Tract Infection in Nigerian Under-Five Children: Proposal for a Case-Control Association Study.JMIR research protocols · 2018Article
- Detection of PCT and urinary βJournal of clinical laboratory analysis · 2017Article
- Predictive Accuracy of Urinary neutrophil gelatinase associated lipocalin (NGAL) for renal parenchymal involvement in Children with Acute Pyelonephritis.Electronic physician · 2016Article
- [Neurogenic bladder function disorders in patients with meningomyelocele: S2k guidelines on diagnostics and therapy].Der Urologe. Ausg. A · 2015Review
- History of recurrent urinary tract infection is not predictive of abnormality on voiding cystourethrogram.Pediatric surgery international · 2013Article
- [Diagnostics and therapy of urinary tract infections].Der Urologe. Ausg. A · 2013Article
- Umbilical blood biomarkers for predicting early-onset neonatal sepsis.World journal of pediatrics : WJP · 2012Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Urinary tract infections (UTIs) are the most common source of bacterial infections among young febrile children. Accurate diagnosis of acute pyelonephritis (APN) and vesicoureteral reflux (VUR) is important because of their association with renal scarring, leading in the cases to long-term complications. However, the gold standard examinations for both are either DMSA scan (for APN and scar) or cystography (for VUR) and present limitations (feasibility, pain, cost, etc.). Procalcitonin, a reliable marker of bacterial infections, was demonstrated to be a good predictor of both renal parenchymal involvement in the acute phase and late renal scars. Furthermore, it was also found to be associated with high-grade VUR and was the key tool of a clinical decision rule to predict high-grade VUR in children with a first UTI. Therefore, procalcitonin may certainly be found playing a role in the complex and still debated picture of which examination should be performed after UTI in children.
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Registered trials
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